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- W2019851045 abstract "Two families were investigated in which the mothers had selective IgA deficiency and circulating class-specific anti-IgA antibodies. Both gave birth to two children who were found to be IgA deficient. Three of these children developed anti-IgA antibodies before puberty. In vitro immunoglobulin production studies performed in the children of both families revealed an IgA B cell defect combined with IgA-specific excessive T suppressor function in all four. The mechanisms by which transplacental passage of maternal anti-IgA antibodies could have interfered with the developing IgA system in the offspring are discussed." @default.
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- W2019851045 date "1991-01-01" @default.
- W2019851045 modified "2023-09-27" @default.
- W2019851045 title "Familial selective IgA deficiency with circulating anti-IgA antibodies: A distinct group of patients?" @default.
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- W2019851045 doi "https://doi.org/10.1016/0090-1229(91)90151-y" @default.
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