Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019871354> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2019871354 endingPage "e325" @default.
- W2019871354 startingPage "e325" @default.
- W2019871354 abstract "Background: NS1 gene of dengue virus produces a hexameric soluble NS1 protein that is the first viral protein to circulate in host circulation. The viral protein may interact with other human proteins; thus it can be hypothesized to be under selection pressure. Since the probability of molecular heterogeneity is likely in such cases, the present study was carried-out to evaluate the usefulness of the NS1 gene for genotyping of DENV-3 isolated during 2006 major dengue fever outbreak. Methods: Molecular subtyping was performed on eight DENV-3 isolates (sampled in 2006) by comparing with other NS1 sequences reported from India and other parts of the world. For comparison, a 390 bp region from amplified NS1 gene was selected. A phylogenetic tree was constructed by MEGA 3.1 software using Neighbor-Joining method with bootstrap value of 1000 replicates. DENV-3 prototype strain, H-87 was used to root the tree. Results: All the NS1 DENV-3 sequences segregated in 3 distinct genotypes as established on the basis of CprM and E genes in earlier studies; although genotype IV could not be shown due to non-availability of the sequences. Genotype I consisted of viruses isolated in Tahiti, Indonesia and Philippines isolated between 1978–98. Genotype II consisted of viruses from Thailand and Taiwan isolated between 1987–98. Genotype III was further divided in three clades: Indian clade consisting of NS1 2006 and 2005 Indian isolates; American clade consisting of isolates from Martinique and Brazil isolated between 1999–04; and the clade consisting of Singapore (2004–05) and Sri Lanka (2000) isolates. Conclusion: NS1 gene has been found to be useful in molecular subtyping of DEN-3 viruses, although the method has to be evaluated for other circulating dengue virus serotypes." @default.
- W2019871354 created "2016-06-24" @default.
- W2019871354 creator A5014125355 @default.
- W2019871354 creator A5017513211 @default.
- W2019871354 creator A5018015704 @default.
- W2019871354 creator A5023591060 @default.
- W2019871354 creator A5024693699 @default.
- W2019871354 creator A5032786219 @default.
- W2019871354 creator A5039840285 @default.
- W2019871354 creator A5066264366 @default.
- W2019871354 creator A5080440633 @default.
- W2019871354 date "2008-12-01" @default.
- W2019871354 modified "2023-09-27" @default.
- W2019871354 title "Usefulness of NS1 Gene in Molecular Subtyping of Recent Indian Isolates of Dengue Virus Type 3 (DENV-3)" @default.
- W2019871354 doi "https://doi.org/10.1016/j.ijid.2008.05.869" @default.
- W2019871354 hasPublicationYear "2008" @default.
- W2019871354 type Work @default.
- W2019871354 sameAs 2019871354 @default.
- W2019871354 citedByCount "0" @default.
- W2019871354 crossrefType "journal-article" @default.
- W2019871354 hasAuthorship W2019871354A5014125355 @default.
- W2019871354 hasAuthorship W2019871354A5017513211 @default.
- W2019871354 hasAuthorship W2019871354A5018015704 @default.
- W2019871354 hasAuthorship W2019871354A5023591060 @default.
- W2019871354 hasAuthorship W2019871354A5024693699 @default.
- W2019871354 hasAuthorship W2019871354A5032786219 @default.
- W2019871354 hasAuthorship W2019871354A5039840285 @default.
- W2019871354 hasAuthorship W2019871354A5066264366 @default.
- W2019871354 hasAuthorship W2019871354A5080440633 @default.
- W2019871354 hasBestOaLocation W20198713541 @default.
- W2019871354 hasConcept C104317684 @default.
- W2019871354 hasConcept C116675565 @default.
- W2019871354 hasConcept C121332964 @default.
- W2019871354 hasConcept C1276947 @default.
- W2019871354 hasConcept C135763542 @default.
- W2019871354 hasConcept C159047783 @default.
- W2019871354 hasConcept C193252679 @default.
- W2019871354 hasConcept C199360897 @default.
- W2019871354 hasConcept C2549261 @default.
- W2019871354 hasConcept C2779635636 @default.
- W2019871354 hasConcept C2781078984 @default.
- W2019871354 hasConcept C2909528719 @default.
- W2019871354 hasConcept C3018883866 @default.
- W2019871354 hasConcept C31467283 @default.
- W2019871354 hasConcept C41008148 @default.
- W2019871354 hasConcept C44465124 @default.
- W2019871354 hasConcept C533803919 @default.
- W2019871354 hasConcept C54355233 @default.
- W2019871354 hasConcept C83852419 @default.
- W2019871354 hasConcept C86803240 @default.
- W2019871354 hasConcept C95457728 @default.
- W2019871354 hasConcept C97669555 @default.
- W2019871354 hasConceptScore W2019871354C104317684 @default.
- W2019871354 hasConceptScore W2019871354C116675565 @default.
- W2019871354 hasConceptScore W2019871354C121332964 @default.
- W2019871354 hasConceptScore W2019871354C1276947 @default.
- W2019871354 hasConceptScore W2019871354C135763542 @default.
- W2019871354 hasConceptScore W2019871354C159047783 @default.
- W2019871354 hasConceptScore W2019871354C193252679 @default.
- W2019871354 hasConceptScore W2019871354C199360897 @default.
- W2019871354 hasConceptScore W2019871354C2549261 @default.
- W2019871354 hasConceptScore W2019871354C2779635636 @default.
- W2019871354 hasConceptScore W2019871354C2781078984 @default.
- W2019871354 hasConceptScore W2019871354C2909528719 @default.
- W2019871354 hasConceptScore W2019871354C3018883866 @default.
- W2019871354 hasConceptScore W2019871354C31467283 @default.
- W2019871354 hasConceptScore W2019871354C41008148 @default.
- W2019871354 hasConceptScore W2019871354C44465124 @default.
- W2019871354 hasConceptScore W2019871354C533803919 @default.
- W2019871354 hasConceptScore W2019871354C54355233 @default.
- W2019871354 hasConceptScore W2019871354C83852419 @default.
- W2019871354 hasConceptScore W2019871354C86803240 @default.
- W2019871354 hasConceptScore W2019871354C95457728 @default.
- W2019871354 hasConceptScore W2019871354C97669555 @default.
- W2019871354 hasLocation W20198713541 @default.
- W2019871354 hasOpenAccess W2019871354 @default.
- W2019871354 hasPrimaryLocation W20198713541 @default.
- W2019871354 hasRelatedWork W1753239082 @default.
- W2019871354 hasRelatedWork W2011714939 @default.
- W2019871354 hasRelatedWork W2019871354 @default.
- W2019871354 hasRelatedWork W2097959479 @default.
- W2019871354 hasRelatedWork W2131691724 @default.
- W2019871354 hasRelatedWork W2145021899 @default.
- W2019871354 hasRelatedWork W2166268994 @default.
- W2019871354 hasRelatedWork W2415353422 @default.
- W2019871354 hasRelatedWork W3120208084 @default.
- W2019871354 hasRelatedWork W3157502171 @default.
- W2019871354 hasVolume "12" @default.
- W2019871354 isParatext "false" @default.
- W2019871354 isRetracted "false" @default.
- W2019871354 magId "2019871354" @default.
- W2019871354 workType "article" @default.