Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019888404> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2019888404 endingPage "533" @default.
- W2019888404 startingPage "524" @default.
- W2019888404 abstract "There is controversy regarding whether an incremental increase in hemoglobin levels is associated with improvements in health-related quality of life (HRQOL) in chronic kidney disease (CKD) patients treated with erythropoiesis-stimulating agents (ESAs). We hypothesized that HRQOL in anemic CKD patients has a multifactorial etiology, including the effects of anemia and inflammation.69 non-dialysis CKD patients over 18 years of age with a mean estimated glomerular filtration rate (eGFR) of 43.7 ± 28.8 ml/min/1.73 m2 were divided into anemic and non-anemic cohorts. Kidney disease quality of life (KDQOL) was prospectively recorded using Short Form (SF)-36 components of KDQOL-SF-™ version 1.3 questionnaire. Inflammation was assessed by using a composite of interleukin (IL)-6, IL-8 and tumor necrosis factor (TNF)-α levels in the upper two quartiles.Anemic patients had significantly worse SF-36 components of KDQOL-SF-™ version 1.3, including SF-12 mental component (p = 0.02), role emotional (p = 0.002) and physical function (p = 0.01) compared to patients without anemia. However, in multiple linear regression models, adjusted for GFR, age, gender and inflammatory markers including C-reactive protein (CRP), albumin, ferritin, IL-6, IL-8 and TNF-α, anemia predicted mental components of SF-36 (SF-12 mental component (p = 0.02) and role emotional (p = 0.04)) but not physical components (SF-12 physical component (p > 0.05) and physical function (p > 0.05), supporting the multifactorial nature of reduced HRQOL in anemic patients.Reduced HRQOL in anemic patients is likely related to both anemic and inflammatory status. Prospective studies will be needed to evaluate whether modulating the inflammatory state independent of changes in the hemoglobin concentration improves physical components of HRQOL." @default.
- W2019888404 created "2016-06-24" @default.
- W2019888404 creator A5007237082 @default.
- W2019888404 creator A5033745812 @default.
- W2019888404 creator A5040257052 @default.
- W2019888404 creator A5052036981 @default.
- W2019888404 creator A5062830831 @default.
- W2019888404 creator A5064980695 @default.
- W2019888404 creator A5066548359 @default.
- W2019888404 date "2011-06-01" @default.
- W2019888404 modified "2023-09-26" @default.
- W2019888404 title "Anemia, inflammation and health-related quality of life in chronic kidney disease patients" @default.
- W2019888404 doi "https://doi.org/10.5414/cnp75524" @default.
- W2019888404 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21612756" @default.
- W2019888404 hasPublicationYear "2011" @default.
- W2019888404 type Work @default.
- W2019888404 sameAs 2019888404 @default.
- W2019888404 citedByCount "38" @default.
- W2019888404 countsByYear W20198884042012 @default.
- W2019888404 countsByYear W20198884042013 @default.
- W2019888404 countsByYear W20198884042014 @default.
- W2019888404 countsByYear W20198884042015 @default.
- W2019888404 countsByYear W20198884042016 @default.
- W2019888404 countsByYear W20198884042017 @default.
- W2019888404 countsByYear W20198884042018 @default.
- W2019888404 countsByYear W20198884042019 @default.
- W2019888404 countsByYear W20198884042020 @default.
- W2019888404 countsByYear W20198884042021 @default.
- W2019888404 countsByYear W20198884042022 @default.
- W2019888404 crossrefType "journal-article" @default.
- W2019888404 hasAuthorship W2019888404A5007237082 @default.
- W2019888404 hasAuthorship W2019888404A5033745812 @default.
- W2019888404 hasAuthorship W2019888404A5040257052 @default.
- W2019888404 hasAuthorship W2019888404A5052036981 @default.
- W2019888404 hasAuthorship W2019888404A5062830831 @default.
- W2019888404 hasAuthorship W2019888404A5064980695 @default.
- W2019888404 hasAuthorship W2019888404A5066548359 @default.
- W2019888404 hasConcept C126322002 @default.
- W2019888404 hasConcept C159110408 @default.
- W2019888404 hasConcept C159641895 @default.
- W2019888404 hasConcept C2778248108 @default.
- W2019888404 hasConcept C2778319317 @default.
- W2019888404 hasConcept C2778653478 @default.
- W2019888404 hasConcept C2778917026 @default.
- W2019888404 hasConcept C2779951463 @default.
- W2019888404 hasConcept C2779978075 @default.
- W2019888404 hasConcept C71924100 @default.
- W2019888404 hasConcept C90924648 @default.
- W2019888404 hasConceptScore W2019888404C126322002 @default.
- W2019888404 hasConceptScore W2019888404C159110408 @default.
- W2019888404 hasConceptScore W2019888404C159641895 @default.
- W2019888404 hasConceptScore W2019888404C2778248108 @default.
- W2019888404 hasConceptScore W2019888404C2778319317 @default.
- W2019888404 hasConceptScore W2019888404C2778653478 @default.
- W2019888404 hasConceptScore W2019888404C2778917026 @default.
- W2019888404 hasConceptScore W2019888404C2779951463 @default.
- W2019888404 hasConceptScore W2019888404C2779978075 @default.
- W2019888404 hasConceptScore W2019888404C71924100 @default.
- W2019888404 hasConceptScore W2019888404C90924648 @default.
- W2019888404 hasIssue "06" @default.
- W2019888404 hasLocation W20198884041 @default.
- W2019888404 hasLocation W20198884042 @default.
- W2019888404 hasOpenAccess W2019888404 @default.
- W2019888404 hasPrimaryLocation W20198884041 @default.
- W2019888404 hasRelatedWork W1786582985 @default.
- W2019888404 hasRelatedWork W1999577714 @default.
- W2019888404 hasRelatedWork W202168480 @default.
- W2019888404 hasRelatedWork W2051682319 @default.
- W2019888404 hasRelatedWork W2152354994 @default.
- W2019888404 hasRelatedWork W2567256464 @default.
- W2019888404 hasRelatedWork W2947318399 @default.
- W2019888404 hasRelatedWork W4297448048 @default.
- W2019888404 hasRelatedWork W4365511089 @default.
- W2019888404 hasRelatedWork W4377820566 @default.
- W2019888404 hasVolume "75" @default.
- W2019888404 isParatext "false" @default.
- W2019888404 isRetracted "false" @default.
- W2019888404 magId "2019888404" @default.
- W2019888404 workType "article" @default.