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• W2019895813 endingPage "d849" @default.
• W2019895813 startingPage "d849" @default.
• W2019895813 abstract "PCNA (proliferating cell nuclear antigen), originally characterized as a DNA polymerase accessory protein, functions as a DNA sliding clamp for DNA polymerase delta and is an essential component for eukaryotic chromosomal DNA replication. Recent studies have revealed a striking feature of PCNA in its ability to interact with multiple partners, involved, for example, in Okazaki fragment joining, DNA repair, DNA methylation and chromatin assembly. Since these reactions take place mainly on replicating DNA, PCNA has applications as a marker for DNA synthesis. It is of interest that proteins involved in cell cycle regulation may also exhibit PCNA binding activity. For example, the CDK inhibitor, p21 (Cip1/Waf1) interacts with PCNA blocking its activity necessary for DNA replication and also affecting interactions with other PCNA binding proteins. The available data indicate that DNA sliding clamps have generated additional functions with evolution of eukaryotes from simple prokaryotes. In mammalian cells, they play key roles in controlling DNA synthesis reactions and the reorganization of replicated DNA at replication forks. Several cell cycle regulation proteins target these processes by affecting PCNA actions." @default.
• W2019895813 created "2016-06-24" @default.
• W2019895813 creator A5012507568 @default.
• W2019895813 date "1999-01-01" @default.
• W2019895813 modified "2023-10-16" @default.
• W2019895813 title "PCNA binding proteins" @default.
• W2019895813 cites W1506492200 @default.
• W2019895813 cites W1517952165 @default.
• W2019895813 cites W1536976216 @default.
• W2019895813 cites W1551254087 @default.
• W2019895813 cites W1552586455 @default.
• W2019895813 cites W1561028677 @default.
• W2019895813 cites W1561042802 @default.
• W2019895813 cites W1574197136 @default.
• W2019895813 cites W1587273245 @default.
• W2019895813 cites W1600623344 @default.
• W2019895813 cites W1866839234 @default.
• W2019895813 cites W1908345703 @default.
• W2019895813 cites W1919026068 @default.
• W2019895813 cites W1967880575 @default.
• W2019895813 cites W1972743742 @default.
• W2019895813 cites W1974062601 @default.
• W2019895813 cites W1975098427 @default.
• W2019895813 cites W1979697079 @default.
• W2019895813 cites W1979781336 @default.
• W2019895813 cites W1984415680 @default.
• W2019895813 cites W1987081708 @default.
• W2019895813 cites W1988134858 @default.
• W2019895813 cites W1988762859 @default.
• W2019895813 cites W1992082799 @default.
• W2019895813 cites W1993073412 @default.
• W2019895813 cites W1994051286 @default.
• W2019895813 cites W1994245744 @default.
• W2019895813 cites W1995719245 @default.
• W2019895813 cites W2003245647 @default.
• W2019895813 cites W2003282728 @default.
• W2019895813 cites W2012291005 @default.
• W2019895813 cites W2015066175 @default.
• W2019895813 cites W2020633581 @default.
• W2019895813 cites W2021345772 @default.
• W2019895813 cites W2025163738 @default.
• W2019895813 cites W2029169816 @default.
• W2019895813 cites W2029309152 @default.
• W2019895813 cites W2029440030 @default.
• W2019895813 cites W2035932182 @default.
• W2019895813 cites W2037987328 @default.
• W2019895813 cites W2038149991 @default.
• W2019895813 cites W2040115433 @default.
• W2019895813 cites W2040135708 @default.
• W2019895813 cites W2040150820 @default.
• W2019895813 cites W2041249795 @default.
• W2019895813 cites W2042531267 @default.
• W2019895813 cites W2045590352 @default.
• W2019895813 cites W2046386929 @default.
• W2019895813 cites W2049528447 @default.
• W2019895813 cites W2052540561 @default.
• W2019895813 cites W2055348937 @default.
• W2019895813 cites W2060769308 @default.
• W2019895813 cites W2062300934 @default.
• W2019895813 cites W2062795729 @default.
• W2019895813 cites W2063995526 @default.
• W2019895813 cites W2064477710 @default.
• W2019895813 cites W2065014822 @default.
• W2019895813 cites W2072489106 @default.
• W2019895813 cites W2076273397 @default.
• W2019895813 cites W2078690152 @default.
• W2019895813 cites W2081290278 @default.
• W2019895813 cites W2088867782 @default.
• W2019895813 cites W2090695231 @default.
• W2019895813 cites W2090903262 @default.
• W2019895813 cites W2091790979 @default.
• W2019895813 cites W2092713502 @default.
• W2019895813 cites W2094292611 @default.
• W2019895813 cites W2094585804 @default.
• W2019895813 cites W2105272116 @default.
• W2019895813 cites W2111105553 @default.
• W2019895813 cites W2114688186 @default.
• W2019895813 cites W2116537286 @default.
• W2019895813 cites W2120917736 @default.
• W2019895813 cites W2122748184 @default.
• W2019895813 cites W2123024247 @default.
• W2019895813 cites W2123985521 @default.
• W2019895813 cites W2124350341 @default.
• W2019895813 cites W2127316404 @default.
• W2019895813 cites W2135158692 @default.
• W2019895813 cites W2139316119 @default.
• W2019895813 cites W2142485616 @default.
• W2019895813 cites W2146279188 @default.
• W2019895813 cites W2154690470 @default.
• W2019895813 cites W2154949704 @default.
• W2019895813 cites W2159531864 @default.
• W2019895813 cites W2163864783 @default.
• W2019895813 cites W2165181073 @default.
• W2019895813 cites W2169437718 @default.
• W2019895813 cites W2171367003 @default.
• W2019895813 cites W235836333 @default.
• W2019895813 cites W84014835 @default.
• W2019895813 doi "https://doi.org/10.2741/tsurimoto" @default.

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