Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019898797> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2019898797 endingPage "671" @default.
- W2019898797 startingPage "666" @default.
- W2019898797 abstract "Eighteen eyes of 15 patients with uncontrolled glaucoma (neovascular, intracapsular aphakia, uveitic, previous filtration failure) at high risk for failure of standard filtration underwent trabeculectomy with implantation of a purified collagen sponge containing 100 μg of antimetabolite (5-fluorouracil or bleomycin). Follow-up ranged from 3 months to 5 years. At the end of follow-up, 14 eyes (78%) had intraocular pressure below 21 mmHg and functional filtration blebs. No corneal toxicity was encountered at any time. Two patients (both successes) had partial or complete erosion of the collagen sponge. Although the differences were not statistically significant, patients receiving bleomycin had better success rates (8 of 9 versus 6 of 9) and lower intraocular pressure levels (11.88 mmHg versus 14.63 mmHg) than those receiving 5-fluorouracil. The collagen sponge implant demonstrates the clear advantages of drug delivery devices for the administration of antimetabolites after filtration surgery. Eighteen eyes of 15 patients with uncontrolled glaucoma (neovascular, intracapsular aphakia, uveitic, previous filtration failure) at high risk for failure of standard filtration underwent trabeculectomy with implantation of a purified collagen sponge containing 100 μg of antimetabolite (5-fluorouracil or bleomycin). Follow-up ranged from 3 months to 5 years. At the end of follow-up, 14 eyes (78%) had intraocular pressure below 21 mmHg and functional filtration blebs. No corneal toxicity was encountered at any time. Two patients (both successes) had partial or complete erosion of the collagen sponge. Although the differences were not statistically significant, patients receiving bleomycin had better success rates (8 of 9 versus 6 of 9) and lower intraocular pressure levels (11.88 mmHg versus 14.63 mmHg) than those receiving 5-fluorouracil. The collagen sponge implant demonstrates the clear advantages of drug delivery devices for the administration of antimetabolites after filtration surgery." @default.
- W2019898797 created "2016-06-24" @default.
- W2019898797 creator A5000306996 @default.
- W2019898797 date "1992-05-01" @default.
- W2019898797 modified "2023-09-25" @default.
- W2019898797 title "Long-term Results of Trabeculectomy with Collagen Sponge Implant Containing Low-dose Antimetabolite" @default.
- W2019898797 cites W145220785 @default.
- W2019898797 cites W1977149291 @default.
- W2019898797 cites W1989215939 @default.
- W2019898797 cites W1997487881 @default.
- W2019898797 cites W2017992423 @default.
- W2019898797 cites W2029997539 @default.
- W2019898797 cites W2047104496 @default.
- W2019898797 cites W2050573917 @default.
- W2019898797 cites W2229944160 @default.
- W2019898797 cites W2240745707 @default.
- W2019898797 cites W2395407914 @default.
- W2019898797 cites W316895702 @default.
- W2019898797 doi "https://doi.org/10.1016/s0161-6420(92)31919-0" @default.
- W2019898797 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1375713" @default.
- W2019898797 hasPublicationYear "1992" @default.
- W2019898797 type Work @default.
- W2019898797 sameAs 2019898797 @default.
- W2019898797 citedByCount "12" @default.
- W2019898797 countsByYear W20198987972012 @default.
- W2019898797 countsByYear W20198987972013 @default.
- W2019898797 countsByYear W20198987972016 @default.
- W2019898797 crossrefType "journal-article" @default.
- W2019898797 hasAuthorship W2019898797A5000306996 @default.
- W2019898797 hasConcept C118487528 @default.
- W2019898797 hasConcept C141071460 @default.
- W2019898797 hasConcept C2776232574 @default.
- W2019898797 hasConcept C2776694085 @default.
- W2019898797 hasConcept C2777345934 @default.
- W2019898797 hasConcept C2777824320 @default.
- W2019898797 hasConcept C2778257484 @default.
- W2019898797 hasConcept C2778397455 @default.
- W2019898797 hasConcept C2778527774 @default.
- W2019898797 hasConcept C2781092963 @default.
- W2019898797 hasConcept C2781411149 @default.
- W2019898797 hasConcept C71924100 @default.
- W2019898797 hasConceptScore W2019898797C118487528 @default.
- W2019898797 hasConceptScore W2019898797C141071460 @default.
- W2019898797 hasConceptScore W2019898797C2776232574 @default.
- W2019898797 hasConceptScore W2019898797C2776694085 @default.
- W2019898797 hasConceptScore W2019898797C2777345934 @default.
- W2019898797 hasConceptScore W2019898797C2777824320 @default.
- W2019898797 hasConceptScore W2019898797C2778257484 @default.
- W2019898797 hasConceptScore W2019898797C2778397455 @default.
- W2019898797 hasConceptScore W2019898797C2778527774 @default.
- W2019898797 hasConceptScore W2019898797C2781092963 @default.
- W2019898797 hasConceptScore W2019898797C2781411149 @default.
- W2019898797 hasConceptScore W2019898797C71924100 @default.
- W2019898797 hasIssue "5" @default.
- W2019898797 hasLocation W20198987971 @default.
- W2019898797 hasLocation W20198987972 @default.
- W2019898797 hasOpenAccess W2019898797 @default.
- W2019898797 hasPrimaryLocation W20198987971 @default.
- W2019898797 hasRelatedWork W1995026213 @default.
- W2019898797 hasRelatedWork W2019898797 @default.
- W2019898797 hasRelatedWork W2022049485 @default.
- W2019898797 hasRelatedWork W2046981428 @default.
- W2019898797 hasRelatedWork W2055481464 @default.
- W2019898797 hasRelatedWork W2261410949 @default.
- W2019898797 hasRelatedWork W3158705813 @default.
- W2019898797 hasRelatedWork W4214577541 @default.
- W2019898797 hasRelatedWork W4317215083 @default.
- W2019898797 hasRelatedWork W74882172 @default.
- W2019898797 hasVolume "99" @default.
- W2019898797 isParatext "false" @default.
- W2019898797 isRetracted "false" @default.
- W2019898797 magId "2019898797" @default.
- W2019898797 workType "article" @default.