FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019900585> ?p ?o ?g. }

• W2019900585 endingPage "14" @default.
• W2019900585 startingPage "8" @default.
• W2019900585 abstract "Abstract Purpose of the research: Tooth germ development involves multiple events, including cell proliferation and cell differentiation. Connective tissue growth factor (CTGF/CCN2) is a signaling protein involved in tooth germ development, and we investigated how it is expressed and what roles it may have in primary cultures of mesenchymal cells derived from the developing tooth germ. We also examined the expression of CCN2 in a human odontogenic myxofibroma, a benign tumor of odontogenic mesenchymal origin, and considered the possible roles of CCN2 in the development of myxofibromas. Materials and methods: Mesenchymal cells of early bell‐stage tooth germs were isolated from Day‐90 bovine embryos and placed in primary culture. A resected specimen from a patient with odontogenic myxofibroma was prepared for immunohistochemical studies. Principal results: The CCN2 expression level in proliferating odontogenic mesenchymal cells freshly isolated from the early bell stage of developing bovine tooth germs and placed in primary culture was 3 times higher than that in the confluent non‐proliferating cells. Recombinant CCN2 significantly increased the proliferation and type I collagen expression in odontogenic mesenchymal cells in primary culture. Immunohistochemical analysis on myxofibroma case revealed that CCN2 was detectable in MIB‐1, a cellular marker of proliferation‐positive odontogenic mesenchymal cells adjacent to capillary blood vessels and in the endothelial cells of the vessels in the tumor. Major conclusion: CCN2 signaling would influence the proliferation of and extracellular matrix production by dental mesenchymal cells. Our results suggest that the same mechanisms of CCN2 action toward dental mesenchymal cells would also be operative in the odontogenic myxofibroma microenvironment." @default.
• W2019900585 created "2016-06-24" @default.
• W2019900585 creator A5014468079 @default.
• W2019900585 creator A5015429847 @default.
• W2019900585 creator A5026819474 @default.
• W2019900585 creator A5037500648 @default.
• W2019900585 creator A5045949618 @default.
• W2019900585 creator A5048999826 @default.
• W2019900585 creator A5056064939 @default.
• W2019900585 creator A5058063773 @default.
• W2019900585 creator A5071604185 @default.
• W2019900585 creator A5081164873 @default.
• W2019900585 creator A5090078880 @default.
• W2019900585 creator A5091655217 @default.
• W2019900585 date "2013-03-29" @default.
• W2019900585 modified "2023-09-25" @default.
• W2019900585 title "Expression and roles of CCN2 in dental mesenchymal cells in primary culture—With findings in a case of odontogenic myxofibroma" @default.
• W2019900585 cites W1539672372 @default.
• W2019900585 cites W1703909136 @default.
• W2019900585 cites W1963681955 @default.
• W2019900585 cites W1978123102 @default.
• W2019900585 cites W1984320235 @default.
• W2019900585 cites W1992479775 @default.
• W2019900585 cites W1999692369 @default.
• W2019900585 cites W2026911239 @default.
• W2019900585 cites W2038448289 @default.
• W2019900585 cites W2042249648 @default.
• W2019900585 cites W2044287672 @default.
• W2019900585 cites W2045331305 @default.
• W2019900585 cites W2047445763 @default.
• W2019900585 cites W2069106746 @default.
• W2019900585 cites W2080211548 @default.
• W2019900585 cites W2106232223 @default.
• W2019900585 cites W2108345823 @default.
• W2019900585 cites W2116588084 @default.
• W2019900585 cites W2118271430 @default.
• W2019900585 cites W2124681664 @default.
• W2019900585 cites W2131392813 @default.
• W2019900585 cites W2134734822 @default.
• W2019900585 cites W2158956432 @default.
• W2019900585 cites W2163076834 @default.
• W2019900585 cites W4237959803 @default.
• W2019900585 doi "https://doi.org/10.1016/s1348-8643(13)00008-6" @default.
• W2019900585 hasPublicationYear "2013" @default.
• W2019900585 type Work @default.
• W2019900585 sameAs 2019900585 @default.
• W2019900585 citedByCount "1" @default.
• W2019900585 countsByYear W20199005852016 @default.
• W2019900585 crossrefType "journal-article" @default.
• W2019900585 hasAuthorship W2019900585A5014468079 @default.
• W2019900585 hasAuthorship W2019900585A5015429847 @default.
• W2019900585 hasAuthorship W2019900585A5026819474 @default.
• W2019900585 hasAuthorship W2019900585A5037500648 @default.
• W2019900585 hasAuthorship W2019900585A5045949618 @default.
• W2019900585 hasAuthorship W2019900585A5048999826 @default.
• W2019900585 hasAuthorship W2019900585A5056064939 @default.
• W2019900585 hasAuthorship W2019900585A5058063773 @default.
• W2019900585 hasAuthorship W2019900585A5071604185 @default.
• W2019900585 hasAuthorship W2019900585A5081164873 @default.
• W2019900585 hasAuthorship W2019900585A5090078880 @default.
• W2019900585 hasAuthorship W2019900585A5091655217 @default.
• W2019900585 hasBestOaLocation W20199005852 @default.
• W2019900585 hasConcept C142724271 @default.
• W2019900585 hasConcept C170493617 @default.
• W2019900585 hasConcept C189165786 @default.
• W2019900585 hasConcept C198826908 @default.
• W2019900585 hasConcept C2775960820 @default.
• W2019900585 hasConcept C2780631158 @default.
• W2019900585 hasConcept C518705261 @default.
• W2019900585 hasConcept C54355233 @default.
• W2019900585 hasConcept C55493867 @default.
• W2019900585 hasConcept C62112901 @default.
• W2019900585 hasConcept C71924100 @default.
• W2019900585 hasConcept C86803240 @default.
• W2019900585 hasConcept C95444343 @default.
• W2019900585 hasConceptScore W2019900585C142724271 @default.
• W2019900585 hasConceptScore W2019900585C170493617 @default.
• W2019900585 hasConceptScore W2019900585C189165786 @default.
• W2019900585 hasConceptScore W2019900585C198826908 @default.
• W2019900585 hasConceptScore W2019900585C2775960820 @default.
• W2019900585 hasConceptScore W2019900585C2780631158 @default.
• W2019900585 hasConceptScore W2019900585C518705261 @default.
• W2019900585 hasConceptScore W2019900585C54355233 @default.
• W2019900585 hasConceptScore W2019900585C55493867 @default.
• W2019900585 hasConceptScore W2019900585C62112901 @default.
• W2019900585 hasConceptScore W2019900585C71924100 @default.
• W2019900585 hasConceptScore W2019900585C86803240 @default.
• W2019900585 hasConceptScore W2019900585C95444343 @default.
• W2019900585 hasIssue "1" @default.
• W2019900585 hasLocation W20199005851 @default.
• W2019900585 hasLocation W20199005852 @default.
• W2019900585 hasOpenAccess W2019900585 @default.
• W2019900585 hasPrimaryLocation W20199005851 @default.
• W2019900585 hasRelatedWork W1577040882 @default.
• W2019900585 hasRelatedWork W2019506321 @default.
• W2019900585 hasRelatedWork W2028104308 @default.
• W2019900585 hasRelatedWork W2029717792 @default.
• W2019900585 hasRelatedWork W2131861298 @default.

• next