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- W2019901819 abstract "A series of pyrazoloquinolines, possessing (hetero)arylhydroxymethyl substituents at the quinoline C-4 position were evaluated as PDE10A inhibitors. Among these, methylpyrimidyl analogue 15 was identified as having good rodent and monkey exposure, and a MED of 10 mg/kg in an in vivo model." @default.
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- W2019901819 date "2012-02-01" @default.
- W2019901819 modified "2023-09-27" @default.
- W2019901819 title "Pyrazoloquinolines as PDE10A inhibitors: Discovery of a tool compound" @default.
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- W2019901819 doi "https://doi.org/10.1016/j.bmcl.2011.12.080" @default.
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