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- W2019905106 abstract "Several recent studies demonstrate that adrenergic receptor stimulation evokes marked changes in Mg2+ homeostasis. As insulin counter-regulates many of the metabolic consequences of adrenergic receptor stimulation, we evaluated the potential influence of insulin on Mg2+ movements in response to adrenergic stimulation. The data demonstrate that insulin is able to block the Mg2+ efflux from perfused rat livers stimulated by isoproterenol or 8-Br-cAMP, but has little or no effect on epinephrine or phenylephrine induced Mg2+ efflux. Thus, evidence is provided demonstrating that there are redundant adrenergic pathways regulating Mg2+ efflux from liver tissue. One of these pathways, the beta-adrenergic component, is selectively blocked by insulin. Furthermore, these findings may provide a cellular explanation for hypomagnesemia associated with diabetes." @default.
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- W2019905106 date "1996-10-21" @default.
- W2019905106 modified "2023-09-26" @default.
- W2019905106 title "Regulation of Mg<sup>2+</sup>homeostasis by insulin in perfused rat livers and isolated hepatocytes" @default.
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- W2019905106 doi "https://doi.org/10.1016/0014-5793(96)01051-4" @default.
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