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• W2019907869 abstract "We report integrated nanopore/microfluidic devices in which the unique combination of low pore density, conical nanopore membranes with microfluidic channels created addressable, localized high-field regions for electrophoretic and dielectrophoretic trapping of particles. A poly(ethylene terephthalate) track-etched membrane containing conical pores ∼130 nm in diameter at the tip and ∼1 μm in diameter at the base was used as an interconnect between two perpendicular poly(dimethylsiloxane) microfluidic channels. Integration of the nanopore membrane with microfluidic channels allowed for easy coupling of the electrical potentials and for directed transport of the analyte particles, 200 nm and 1 μm polystyrene microspheres and Caulobacter crescentus bacteria, to the trapping region. Square waves applied to the device generated electric field strengths up to 1.3 × 105 V/cm at the tips of the nanopores in the microchannel intersection. By varying the applied potentials from ±10 to ±100 V and exploring frequencies from dc to 100 kHz, we determined the contributions of electrophoretic and dielectrophoretic forces to the trapping and concentration process. These results suggest that tunable filter elements can be constructed in which the nanoporous elements provide a physical barrier and the applied ac field enhanced selectivity." @default.
• W2019907869 created "2016-06-24" @default.
• W2019907869 creator A5034346589 @default.
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• W2019907869 date "2008-01-08" @default.
• W2019907869 modified "2023-09-23" @default.
• W2019907869 title "Integrated Nanopore/Microchannel Devices for ac Electrokinetic Trapping of Particles" @default.
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• W2019907869 doi "https://doi.org/10.1021/ac701759f" @default.
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