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- W2019912237 abstract "A series of scutellarin-cyclodextrin conjugates (SCU-CD conjugates), in which scutellarin was covalently bound to one of the primary hydroxyl groups of β-CD, were prepared, and their structures were determined using NMR and MS. These conjugates were further characterized by XRD and TG. The results showed that the aqueous solubility of the conjugates was much higher than that of scutellarin, and the conjugates could hardly be hydrolyzed to scutellarin in aqueous solutions. The cytotoxicity of SCU-CD conjugates on human colon cancer cell lines HT-29, SW480, Lovo and HTC116 indicated that the antitumor activities of the conjugates were better than that of scutellarin. This high antitumor activity, along with the satisfactory aqueous solubility and high stability of the conjugates, will be potentially useful for their application on human colon cancer chemotherapies." @default.
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- W2019912237 date "2013-02-01" @default.
- W2019912237 modified "2023-10-18" @default.
- W2019912237 title "Scutellarin-cyclodextrin conjugates: Synthesis, characterization and anticancer activity" @default.
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- W2019912237 doi "https://doi.org/10.1016/j.carbpol.2012.10.012" @default.
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