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- W2019913530 abstract "Abstract A UV spectroscopic method for the simultaneous determination of procaine hydrochloride and phenazone in eardrops was developed. The individual concentrations were calculated by means of a previously described algorithm (using factors based on absorbance ratios) bundled to the computer-aided apparatus. The selected wavelengths were 290 and 242 nm, corresponding to the λ max of procaine hydrochloride and phenazone, respectively. The method allows rapid and accurate determination of the binary mixture m the tested concentration range of 2–9 μg ml −1 for procaine hydrochloride and 10–40 μg ml −1 for phenazone, with a relative standard deviation of less than 1.8%. Second-order derivative spectroscopy and zero-crossing derivative methodology were tested but were found to be unsuitable in this case." @default.
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- W2019913530 date "1990-10-01" @default.
- W2019913530 modified "2023-09-29" @default.
- W2019913530 title "Simultaneous UV spectrophotometric determination of procaine hydrochloride and phenazone in an otic formulation" @default.
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- W2019913530 doi "https://doi.org/10.1016/0378-5173(90)90274-8" @default.
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