Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019920078> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2019920078 endingPage "128" @default.
- W2019920078 startingPage "119" @default.
- W2019920078 abstract "Abstract Low-substituted hydroxypropyl cellulose (L-HPC) was used as a binder and disintegrant in granulation and tabletting. The influences of L-HPC on the extrusion process and the characteristics of pellets prepared by extrusion/spheronization were studied. In one trial the type of L-HPC was varied, in a second the amount of L-HPC LH 20. In both trials pellets were manufactured using different quantities of granulation fluid. Depending on the formulation a working range for water contents leading to beads was defined. In the upper part of the working range the quality of the spheres was good in terms of aspect ratio and sphericity. However, the dissolution rate was found to decrease as the water content of the extrudate increased. All types of L-HPC accelerated the dissolution of acetaminophen. There was no strong correlation between porosity and dissolution time, but increasing porosity tended to lead to faster dissolution. Pellets without L-HPC combined low dissolution rate with low porosity while those with L-HPC LH 20 showed the highest dissolution rate and the greatest porosity." @default.
- W2019920078 created "2016-06-24" @default.
- W2019920078 creator A5053426503 @default.
- W2019920078 date "1993-07-01" @default.
- W2019920078 modified "2023-09-25" @default.
- W2019920078 title "Application of low substituted hydroxypropylcellulose (L-HPC) in the production of pellets using extrusion/spheronization" @default.
- W2019920078 cites W1990859042 @default.
- W2019920078 cites W2029894319 @default.
- W2019920078 cites W2039252531 @default.
- W2019920078 cites W2051519566 @default.
- W2019920078 cites W2057689461 @default.
- W2019920078 cites W2072886272 @default.
- W2019920078 cites W2082002173 @default.
- W2019920078 cites W2090884411 @default.
- W2019920078 doi "https://doi.org/10.1016/0378-5173(93)90219-6" @default.
- W2019920078 hasPublicationYear "1993" @default.
- W2019920078 type Work @default.
- W2019920078 sameAs 2019920078 @default.
- W2019920078 citedByCount "30" @default.
- W2019920078 countsByYear W20199200782013 @default.
- W2019920078 countsByYear W20199200782014 @default.
- W2019920078 countsByYear W20199200782015 @default.
- W2019920078 countsByYear W20199200782019 @default.
- W2019920078 countsByYear W20199200782020 @default.
- W2019920078 countsByYear W20199200782021 @default.
- W2019920078 countsByYear W20199200782022 @default.
- W2019920078 crossrefType "journal-article" @default.
- W2019920078 hasAuthorship W2019920078A5053426503 @default.
- W2019920078 hasConcept C127413603 @default.
- W2019920078 hasConcept C13965031 @default.
- W2019920078 hasConcept C159985019 @default.
- W2019920078 hasConcept C17923525 @default.
- W2019920078 hasConcept C185592680 @default.
- W2019920078 hasConcept C192562407 @default.
- W2019920078 hasConcept C2778958987 @default.
- W2019920078 hasConcept C2780584874 @default.
- W2019920078 hasConcept C2984430287 @default.
- W2019920078 hasConcept C42360764 @default.
- W2019920078 hasConcept C43617362 @default.
- W2019920078 hasConceptScore W2019920078C127413603 @default.
- W2019920078 hasConceptScore W2019920078C13965031 @default.
- W2019920078 hasConceptScore W2019920078C159985019 @default.
- W2019920078 hasConceptScore W2019920078C17923525 @default.
- W2019920078 hasConceptScore W2019920078C185592680 @default.
- W2019920078 hasConceptScore W2019920078C192562407 @default.
- W2019920078 hasConceptScore W2019920078C2778958987 @default.
- W2019920078 hasConceptScore W2019920078C2780584874 @default.
- W2019920078 hasConceptScore W2019920078C2984430287 @default.
- W2019920078 hasConceptScore W2019920078C42360764 @default.
- W2019920078 hasConceptScore W2019920078C43617362 @default.
- W2019920078 hasIssue "1-3" @default.
- W2019920078 hasLocation W20199200781 @default.
- W2019920078 hasOpenAccess W2019920078 @default.
- W2019920078 hasPrimaryLocation W20199200781 @default.
- W2019920078 hasRelatedWork W1964378243 @default.
- W2019920078 hasRelatedWork W1970607065 @default.
- W2019920078 hasRelatedWork W1990366842 @default.
- W2019920078 hasRelatedWork W2023850491 @default.
- W2019920078 hasRelatedWork W2112804065 @default.
- W2019920078 hasRelatedWork W2376744060 @default.
- W2019920078 hasRelatedWork W2554642125 @default.
- W2019920078 hasRelatedWork W3083975930 @default.
- W2019920078 hasRelatedWork W4206089888 @default.
- W2019920078 hasRelatedWork W2492716613 @default.
- W2019920078 hasVolume "96" @default.
- W2019920078 isParatext "false" @default.
- W2019920078 isRetracted "false" @default.
- W2019920078 magId "2019920078" @default.
- W2019920078 workType "article" @default.