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- W2019920182 abstract "Purpose: We identified the temporal expression of activator protein-1 (AP-1) and matrix metalloproteinases (MMPs) after linoleic acid hydroperoxide (LHP) induction of retinal neovascularization. Methods: After injection of LHP into the vitreous of rabbits, samples were collected for AP-1 binding activity and mRNA for MMP-9 and MMPs activity. AP-1 binding activity was measured by eletrophoretic mobility shift assay. MMP-9 activity was measured by zymography and mRNA by quantitative RT-PCR. Results: AP-1 binding activity was increased at 1–3 hr. MMP-9 mRNA levels were increased at 3 hr in the neural retina and by 12 hr in the retinal pigment epithelium (RPE) layer. MMP-9 proteolytic activity was elevated within the neural retina and within the vitreous and in the RPE-interphotoreceptor matrix (IPM) at 12 hr and peaked at 24 hr or 4 days. Conclusions: LHP increases the transcription factor AP-1 which in turn may regulate retinal MMP-9 synthesis during neovascularization." @default.
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- W2019920182 date "2006-01-01" @default.
- W2019920182 modified "2023-09-22" @default.
- W2019920182 title "Activation of AP-1 and Increased Synthesis of MMP-9 in the Rabbit Retina Induced by Lipid Hydroperoxide" @default.
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- W2019920182 cites W1970029265 @default.
- W2019920182 cites W1970371629 @default.
- W2019920182 cites W1974018871 @default.
- W2019920182 cites W1976126526 @default.
- W2019920182 cites W1981290690 @default.
- W2019920182 cites W1982365221 @default.
- W2019920182 cites W1990208526 @default.
- W2019920182 cites W1995479012 @default.
- W2019920182 cites W1995782914 @default.
- W2019920182 cites W2005328558 @default.
- W2019920182 cites W2006441826 @default.
- W2019920182 cites W2007391140 @default.
- W2019920182 cites W2008786326 @default.
- W2019920182 cites W2009876316 @default.
- W2019920182 cites W2010645787 @default.
- W2019920182 cites W2015532531 @default.
- W2019920182 cites W2015602825 @default.
- W2019920182 cites W2017215522 @default.
- W2019920182 cites W2022543237 @default.
- W2019920182 cites W2024070887 @default.
- W2019920182 cites W2025124971 @default.
- W2019920182 cites W2033788381 @default.
- W2019920182 cites W2036101828 @default.
- W2019920182 cites W2045596041 @default.
- W2019920182 cites W2049220062 @default.
- W2019920182 cites W2051147127 @default.
- W2019920182 cites W2058461613 @default.
- W2019920182 cites W2059841560 @default.
- W2019920182 cites W2062271331 @default.
- W2019920182 cites W2068399278 @default.
- W2019920182 cites W2084060660 @default.
- W2019920182 cites W2086026895 @default.
- W2019920182 cites W2087470647 @default.
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- W2019920182 cites W2090883248 @default.
- W2019920182 cites W2093629370 @default.
- W2019920182 cites W2094277681 @default.
- W2019920182 cites W2100025529 @default.
- W2019920182 cites W2112327424 @default.
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- W2019920182 cites W2135124706 @default.
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- W2019920182 cites W2401342777 @default.
- W2019920182 cites W2402260991 @default.
- W2019920182 cites W263481952 @default.
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- W2019920182 doi "https://doi.org/10.1080/02713680600577780" @default.
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