Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019921788> ?p ?o ?g. }
- W2019921788 endingPage "176" @default.
- W2019921788 startingPage "170" @default.
- W2019921788 abstract "To investigate the effect of stress on interferon (IFN)-γ production by intestinal intraepithelial lymphocytes (IEL), we exposed male C3H/HeN mice to electric foot shock for 30 min a day for 5 consecutive days. Immediately after the final foot shock stress, IEL from small intestine were isolated by Percoll density gradient. The stress induced a marked suppression of IFN-γ production by IEL stimulated with immobilized anti-CD3 mAb and a marked decrease in the proportion of IFN-γ-producing CD3+ IEL or αβTCR+ IEL stimulated with PMA + ionomycin. The αβTCR+ subset was the major cause of stress-induced suppression of IFN-γ production by IEL. Glucocorticoid induced the suppression of IFN-γ production by IEL in vitro, which was reversed by mifepristone (RU486), a glucocorticoid receptor antagonist. In vivo administration of RU486 reversed the stress-induced suppression of IFN-γ production by IEL. In conclusion, repeated foot shock stress suppressed IFN-γ production of IEL by stress-induced elevation of endogenous glucocorticoid. Substantial suppression of the αβTCR+ subset was the major cause of the suppression." @default.
- W2019921788 created "2016-06-24" @default.
- W2019921788 creator A5026777101 @default.
- W2019921788 creator A5028146410 @default.
- W2019921788 creator A5039192130 @default.
- W2019921788 creator A5068017752 @default.
- W2019921788 date "2005-09-01" @default.
- W2019921788 modified "2023-09-23" @default.
- W2019921788 title "Effect of foot shock stress on the interferon-γ production of murine intestinal intraepithelial lymphocytes" @default.
- W2019921788 cites W1482898831 @default.
- W2019921788 cites W1515675646 @default.
- W2019921788 cites W1598999539 @default.
- W2019921788 cites W1612510683 @default.
- W2019921788 cites W1882949371 @default.
- W2019921788 cites W1929192772 @default.
- W2019921788 cites W1980931348 @default.
- W2019921788 cites W1984806978 @default.
- W2019921788 cites W1992291375 @default.
- W2019921788 cites W2015573990 @default.
- W2019921788 cites W2017373133 @default.
- W2019921788 cites W2033059529 @default.
- W2019921788 cites W2040151028 @default.
- W2019921788 cites W2044894161 @default.
- W2019921788 cites W2048321333 @default.
- W2019921788 cites W2057626594 @default.
- W2019921788 cites W2059582599 @default.
- W2019921788 cites W2061021278 @default.
- W2019921788 cites W2063700930 @default.
- W2019921788 cites W2066420512 @default.
- W2019921788 cites W2067683972 @default.
- W2019921788 cites W2085867358 @default.
- W2019921788 cites W2086497632 @default.
- W2019921788 cites W2093692047 @default.
- W2019921788 cites W2099540175 @default.
- W2019921788 cites W2133115875 @default.
- W2019921788 cites W2137595704 @default.
- W2019921788 cites W2144627414 @default.
- W2019921788 cites W2169251485 @default.
- W2019921788 cites W2468466341 @default.
- W2019921788 cites W4240042352 @default.
- W2019921788 cites W4242438960 @default.
- W2019921788 doi "https://doi.org/10.1016/j.imlet.2005.03.011" @default.
- W2019921788 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16154496" @default.
- W2019921788 hasPublicationYear "2005" @default.
- W2019921788 type Work @default.
- W2019921788 sameAs 2019921788 @default.
- W2019921788 citedByCount "13" @default.
- W2019921788 countsByYear W20199217882012 @default.
- W2019921788 countsByYear W20199217882013 @default.
- W2019921788 countsByYear W20199217882015 @default.
- W2019921788 countsByYear W20199217882020 @default.
- W2019921788 crossrefType "journal-article" @default.
- W2019921788 hasAuthorship W2019921788A5026777101 @default.
- W2019921788 hasAuthorship W2019921788A5028146410 @default.
- W2019921788 hasAuthorship W2019921788A5039192130 @default.
- W2019921788 hasAuthorship W2019921788A5068017752 @default.
- W2019921788 hasConcept C126322002 @default.
- W2019921788 hasConcept C134018914 @default.
- W2019921788 hasConcept C152605822 @default.
- W2019921788 hasConcept C203014093 @default.
- W2019921788 hasConcept C2776178377 @default.
- W2019921788 hasConcept C2778826759 @default.
- W2019921788 hasConcept C2779234561 @default.
- W2019921788 hasConcept C2780004078 @default.
- W2019921788 hasConcept C2780841215 @default.
- W2019921788 hasConcept C54355233 @default.
- W2019921788 hasConcept C59493245 @default.
- W2019921788 hasConcept C71924100 @default.
- W2019921788 hasConcept C86803240 @default.
- W2019921788 hasConcept C8891405 @default.
- W2019921788 hasConceptScore W2019921788C126322002 @default.
- W2019921788 hasConceptScore W2019921788C134018914 @default.
- W2019921788 hasConceptScore W2019921788C152605822 @default.
- W2019921788 hasConceptScore W2019921788C203014093 @default.
- W2019921788 hasConceptScore W2019921788C2776178377 @default.
- W2019921788 hasConceptScore W2019921788C2778826759 @default.
- W2019921788 hasConceptScore W2019921788C2779234561 @default.
- W2019921788 hasConceptScore W2019921788C2780004078 @default.
- W2019921788 hasConceptScore W2019921788C2780841215 @default.
- W2019921788 hasConceptScore W2019921788C54355233 @default.
- W2019921788 hasConceptScore W2019921788C59493245 @default.
- W2019921788 hasConceptScore W2019921788C71924100 @default.
- W2019921788 hasConceptScore W2019921788C86803240 @default.
- W2019921788 hasConceptScore W2019921788C8891405 @default.
- W2019921788 hasIssue "2" @default.
- W2019921788 hasLocation W20199217881 @default.
- W2019921788 hasLocation W20199217882 @default.
- W2019921788 hasOpenAccess W2019921788 @default.
- W2019921788 hasPrimaryLocation W20199217881 @default.
- W2019921788 hasRelatedWork W1969091663 @default.
- W2019921788 hasRelatedWork W1969105855 @default.
- W2019921788 hasRelatedWork W1992533206 @default.
- W2019921788 hasRelatedWork W2034583712 @default.
- W2019921788 hasRelatedWork W2035905240 @default.
- W2019921788 hasRelatedWork W2078471485 @default.
- W2019921788 hasRelatedWork W2097516685 @default.
- W2019921788 hasRelatedWork W2306251629 @default.
- W2019921788 hasRelatedWork W4378346933 @default.