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- W2019923861 abstract "Two hundred isolates of Mycobacterium tuberculosis were evaluated for their susceptibility to a newly synthesised quinolone derivative, ER-2, compared with ciprofloxacin, ofloxacin, levofloxacin and moxifloxacin. ER-2 and moxifloxacin showed the greatest activity [MIC for 90% of strains tested (MIC90) = 0.5 μg/mL], although levofloxacin and ciprofloxacin showed good activity with an MIC90 of 1 μg/mL. More importantly, ER-2 showed excellent activity against M. tuberculosis H37Rv both in the lungs and spleen of mice, indicating the potential therapeutic value of ER-2 against M. tuberculosis." @default.
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- W2019923861 date "2009-11-01" @default.
- W2019923861 modified "2023-09-27" @default.
- W2019923861 title "In vitro activities of the newly synthesised ER-2 against clinical isolates of Mycobacterium tuberculosis susceptible or resistant to antituberculosis drugs" @default.
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- W2019923861 doi "https://doi.org/10.1016/j.ijantimicag.2009.06.014" @default.
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