FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019924671> ?p ?o ?g. }

• W2019924671 abstract "It has been suggested that weight change might be associated with certain neuroendocrine abnormalities often observed in patients suffering from a depressive illness. This preliminary study examined whether objective measures of weight change were associated with dexamethasone suppression test (DST) results or plasma levels of thyroid hormones, and whether they correlated with clinical improvement. Specific measures included plasma cortisol following dexamethasone, plasma free thyroxine (T4) and triiodothyronine (T3), as well as anthropometric measures (skinfolds, percentage body fat, body density). The majority of patients (75 per cent) showed some weight gain after treatment. A strong positive correlation was observed between weight gain and plasma tricyclic levels (P<0·005) but only a weak correlation was found between plasma tricyclic levels and therapeutic response (r=0·14). A gender difference was seen in the relationship between weight gain and therapeutic response, with weight gain being associated with less improvement in men and more improvement in women. Therefore, weight gain during treatment may not necessarily indicate clinical improvement for all patients. The only variable that reliably predicted treatment response was free T4. High levels of free T4 prior to treatment were highly correlated with better clinical status as indicated by HAMD scores (r=0·87, P<0·005). Following treatment with imipramine, plasma cortisol levels after dexamethasone administration were reduced in treatment responders but not in nonresponders. Overall, patients that showed the largest decreases in post-dexamethasone cortisol levels from before to after treatment also showed the largest decreases in HAMD total scores (r=0·37) and, especially, somatic anxiety scores (r=0·58, p<0·05). These effects were stronger in women than men. © 1997 John Wiley & Sons, Ltd." @default.
• W2019924671 created "2016-06-24" @default.
• W2019924671 creator A5008252939 @default.
• W2019924671 creator A5022694312 @default.
• W2019924671 creator A5023333664 @default.
• W2019924671 creator A5027246988 @default.
• W2019924671 creator A5036903722 @default.
• W2019924671 creator A5042885630 @default.
• W2019924671 date "1997-11-01" @default.
• W2019924671 modified "2023-09-23" @default.
• W2019924671 title "Neuroendocrine and anthropometric measures in major depression: the effect of antidepressant treatment" @default.
• W2019924671 cites W1602530090 @default.
• W2019924671 cites W1794165588 @default.
• W2019924671 cites W1965075385 @default.
• W2019924671 cites W1974394462 @default.
• W2019924671 cites W1979854738 @default.
• W2019924671 cites W2007055289 @default.
• W2019924671 cites W2017475699 @default.
• W2019924671 cites W2046040522 @default.
• W2019924671 cites W2050525087 @default.
• W2019924671 cites W2063679382 @default.
• W2019924671 cites W2065764524 @default.
• W2019924671 cites W2070739216 @default.
• W2019924671 cites W2071389578 @default.
• W2019924671 cites W2079856328 @default.
• W2019924671 cites W2124333455 @default.
• W2019924671 cites W2410051962 @default.
• W2019924671 cites W2414678313 @default.
• W2019924671 doi "https://doi.org/10.1002/(sici)1099-1077(199711/12)12:6<583::aid-hup925>3.0.co;2-s" @default.
• W2019924671 hasPublicationYear "1997" @default.
• W2019924671 type Work @default.
• W2019924671 sameAs 2019924671 @default.
• W2019924671 citedByCount "1" @default.
• W2019924671 crossrefType "journal-article" @default.
• W2019924671 hasAuthorship W2019924671A5008252939 @default.
• W2019924671 hasAuthorship W2019924671A5022694312 @default.
• W2019924671 hasAuthorship W2019924671A5023333664 @default.
• W2019924671 hasAuthorship W2019924671A5027246988 @default.
• W2019924671 hasAuthorship W2019924671A5036903722 @default.
• W2019924671 hasAuthorship W2019924671A5042885630 @default.
• W2019924671 hasConcept C126322002 @default.
• W2019924671 hasConcept C134018914 @default.
• W2019924671 hasConcept C139719470 @default.
• W2019924671 hasConcept C142724271 @default.
• W2019924671 hasConcept C147583825 @default.
• W2019924671 hasConcept C162324750 @default.
• W2019924671 hasConcept C204787440 @default.
• W2019924671 hasConcept C2776867660 @default.
• W2019924671 hasConcept C2778288131 @default.
• W2019924671 hasConcept C2779145073 @default.
• W2019924671 hasConcept C2779177272 @default.
• W2019924671 hasConcept C2779657639 @default.
• W2019924671 hasConcept C2780221984 @default.
• W2019924671 hasConcept C2780320433 @default.
• W2019924671 hasConcept C2780401358 @default.
• W2019924671 hasConcept C2780455818 @default.
• W2019924671 hasConcept C2781161787 @default.
• W2019924671 hasConcept C61427482 @default.
• W2019924671 hasConcept C71315377 @default.
• W2019924671 hasConcept C71924100 @default.
• W2019924671 hasConceptScore W2019924671C126322002 @default.
• W2019924671 hasConceptScore W2019924671C134018914 @default.
• W2019924671 hasConceptScore W2019924671C139719470 @default.
• W2019924671 hasConceptScore W2019924671C142724271 @default.
• W2019924671 hasConceptScore W2019924671C147583825 @default.
• W2019924671 hasConceptScore W2019924671C162324750 @default.
• W2019924671 hasConceptScore W2019924671C204787440 @default.
• W2019924671 hasConceptScore W2019924671C2776867660 @default.
• W2019924671 hasConceptScore W2019924671C2778288131 @default.
• W2019924671 hasConceptScore W2019924671C2779145073 @default.
• W2019924671 hasConceptScore W2019924671C2779177272 @default.
• W2019924671 hasConceptScore W2019924671C2779657639 @default.
• W2019924671 hasConceptScore W2019924671C2780221984 @default.
• W2019924671 hasConceptScore W2019924671C2780320433 @default.
• W2019924671 hasConceptScore W2019924671C2780401358 @default.
• W2019924671 hasConceptScore W2019924671C2780455818 @default.
• W2019924671 hasConceptScore W2019924671C2781161787 @default.
• W2019924671 hasConceptScore W2019924671C61427482 @default.
• W2019924671 hasConceptScore W2019924671C71315377 @default.
• W2019924671 hasConceptScore W2019924671C71924100 @default.
• W2019924671 hasLocation W20199246711 @default.
• W2019924671 hasOpenAccess W2019924671 @default.
• W2019924671 hasPrimaryLocation W20199246711 @default.
• W2019924671 hasRelatedWork W1982015769 @default.
• W2019924671 hasRelatedWork W2002364072 @default.
• W2019924671 hasRelatedWork W2034528117 @default.
• W2019924671 hasRelatedWork W2074535532 @default.
• W2019924671 hasRelatedWork W2138632275 @default.
• W2019924671 hasRelatedWork W2254368910 @default.
• W2019924671 hasRelatedWork W2274431116 @default.
• W2019924671 hasRelatedWork W2352463487 @default.
• W2019924671 hasRelatedWork W2357525887 @default.
• W2019924671 hasRelatedWork W2358688694 @default.
• W2019924671 hasRelatedWork W2383008050 @default.
• W2019924671 hasRelatedWork W2467048865 @default.
• W2019924671 hasRelatedWork W2472009498 @default.
• W2019924671 hasRelatedWork W3030527771 @default.
• W2019924671 hasRelatedWork W3030627875 @default.
• W2019924671 hasRelatedWork W3032748788 @default.
• W2019924671 hasRelatedWork W3092767089 @default.

• next