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• W2019924845 abstract "The suppressive effect on the postprandial blood glucose rise through alpha-glucosidase (AGH) inhibition was investigated in this study in order to clarify an antihyperglycemic function of 6-O-caffeoylsophorose (CS) from diacylated anthocyanin. The administration of CS (100 mg/kg) following maltose (2 g/kg) to Sprague-Dawley rats resulted in the maximal blood glucose level after 30 min being significantly decreased by 11.1% compared to the control. A reduction in the serum insulin secretion was also observed in parallel to the decrease in blood glucose level. No blood glucose change was apparent when sucrose or glucose was ingested, suggesting that the antihyperglycemic effect of CS was achieved by maltase inhibition, rather than by sucrase or glucose transport inhibition. An AGH inhibitory assay demonstrated that the non-competitive maltase inhibition of CS was partly due to acylation by phenolic acid with sugar, the presence of hydroxyl groups in the aromatic ring, and the presence of an unsaturated alkyl chain in the acylated moiety." @default.
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• W2019924845 date "2004-01-01" @default.
• W2019924845 modified "2023-09-26" @default.
• W2019924845 title "Caffeoylsophorose, a New Natural α-Glucosidase Inhibitor, from Red Vinegar by Fermented Purple-Fleshed Sweet Potato" @default.
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• W2019924845 doi "https://doi.org/10.1271/bbb.68.2239" @default.
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