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- W2019927637 abstract "Bacoside-A (B-A) was evaluated for its hepatoprotective activity against d-GalN induced liver injury in rats. B-A is a major constituent isolated from the plant Bacopa monniera Linn. B-A (10 mg/kg of body weight) was administered orally once daily for 21 days and then d-GalN (300 mg/kg of body weight) was injected on 21st day after final administration of B-A. B-A reduces the elevated levels of serum alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), γ-glutamyl transferase (γ-GT), lactate dehydrogenase (LDH), 5′nucleotidase (5′ND). In addition B-A also significantly restored towards normalization of the decreased levels of Vit-C, and Vit-E induced by d-GalN both in liver and plasma. These results suggest that B-A has hepatoprotective effect against d-GalN induced hepatotxicity in rats." @default.
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- W2019927637 date "2008-10-01" @default.
- W2019927637 modified "2023-09-30" @default.
- W2019927637 title "Hepatoprotective effect of Bacoside-A, a major constituent of Bacopa monniera Linn" @default.
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- W2019927637 doi "https://doi.org/10.1016/j.phymed.2007.11.020" @default.
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