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• W2019929410 abstract "The development of nanoparticle-based dual-modality probes for magnetic resonance imaging (MRI) and positron emission tomography (PET) or single photon emission computed tomography (SPECT) is increasingly growing in importance. One of the most commonly used radionuclides for clinical SPECT imaging is 99mTc and the labelling of Fe3O4 nanoparticles with 99mTc was shown to be a successful strategy to obtain dual-modality imaging agents. In this work, we focus on gold containing magnetic nanomaterials. The radiolabelling of magnetic Fe3O4–Au core–shell and Fe3O4–Au dumbbell-like nanoparticles with the [99mTc(CO)3]+ fragment is described. The key elements for this 99mTc labelling approach are novel coating ligands, consisting of an anchor for the Au surface, a polyethylene glycol linker and a strong chelator for the [99mTc(CO)3]+ moiety." @default.
• W2019929410 created "2016-06-24" @default.
• W2019929410 creator A5048607332 @default.
• W2019929410 creator A5063303431 @default.
• W2019929410 date "2015-01-01" @default.
• W2019929410 modified "2023-09-23" @default.
• W2019929410 title "^99mTc radiolabelling of Fe₃O₄–Au core–shell and Au–Fe₃O₄dumbbell-like nanoparticles" @default.
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• W2019929410 doi "https://doi.org/10.1039/c5nr00269a" @default.
• W2019929410 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25797603" @default.
• W2019929410 hasPublicationYear "2015" @default.
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