FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019932871> ?p ?o ?g. }

• W2019932871 endingPage "328" @default.
• W2019932871 startingPage "323" @default.
• W2019932871 abstract "In hypertension, sodium sensitivity (SS) of blood pressure is associated with renal hemodynamic abnormalities related to increased activity of the renal renin–angiotensin aldosterone system (RAAS). The renal mechanisms of SS in normotensives are unknown. Therefore, we studied whether SS is related to renal hemodynamics and renal responsiveness to angiotensin II (AngII) in young healthy adults. Blood pressure (mean arterial pressure (MAP)) and renal function were measured in 34 healthy men after 1-week low-sodium diet (LS; 50 mmol Na+/24 h), 1-week high-sodium diet (HS; 200 mmol Na+/24h), and 1-week HS-ACEi (enalapril 20 mg/day). The responses of effective renal plasma flow (ERPF; 131I-Hippuran clearance) to graded infusion of AngII were assessed during each condition. The sodium-induced change in MAP ranged from −7 to +14 mm Hg. SS (a sodium-induced increase in MAP >3 mm Hg) was present in 13 subjects. ERPF was lower in SS subjects during LS and during HS-ACEi. The AngII-induced decrease in ERPF was blunted in SS on LS (−25 ± 6 vs. −29 ± 7% in sodium-resistant (SR) subjects, P < 0.05) and on HS (−30 ± 5 vs. −35 ± 6%, P < 0.05). The blunting was corrected by angiotensin-converting enzyme inhibitors (ACEi) (−36 ± 6 vs. −37 ± 7%). SS normotensive subjects have a blunted renal response to exogenous AngII. This is ameliorated by ACEi, supporting a role for inappropriately high intrarenal RAAS activity. As these findings cannot be attributed to subclinical renal hypertensive damage, high intrarenal RAAS activity and altered renal hemodynamics may be primary phenomena underlying SS." @default.
• W2019932871 created "2016-06-24" @default.
• W2019932871 creator A5010367070 @default.
• W2019932871 creator A5024831837 @default.
• W2019932871 creator A5043270519 @default.
• W2019932871 creator A5057033238 @default.
• W2019932871 creator A5063227767 @default.
• W2019932871 date "2008-03-01" @default.
• W2019932871 modified "2023-10-06" @default.
• W2019932871 title "Renal Response to Angiotensin II is Blunted in Sodium-sensitive Normotensive Men" @default.
• W2019932871 cites W1579360182 @default.
• W2019932871 cites W1964875415 @default.
• W2019932871 cites W1973115368 @default.
• W2019932871 cites W1974208490 @default.
• W2019932871 cites W1983953296 @default.
• W2019932871 cites W1993252396 @default.
• W2019932871 cites W2032300827 @default.
• W2019932871 cites W2038421266 @default.
• W2019932871 cites W2044404461 @default.
• W2019932871 cites W2050359833 @default.
• W2019932871 cites W2057107338 @default.
• W2019932871 cites W2060544145 @default.
• W2019932871 cites W2090559153 @default.
• W2019932871 cites W2097847929 @default.
• W2019932871 cites W2099981978 @default.
• W2019932871 cites W2102027896 @default.
• W2019932871 cites W2103235855 @default.
• W2019932871 cites W2108097352 @default.
• W2019932871 cites W2122747902 @default.
• W2019932871 cites W2145808181 @default.
• W2019932871 cites W2151916424 @default.
• W2019932871 cites W2154308741 @default.
• W2019932871 cites W2161963384 @default.
• W2019932871 cites W2166377713 @default.
• W2019932871 cites W2169973185 @default.
• W2019932871 cites W2400662394 @default.
• W2019932871 doi "https://doi.org/10.1038/ajh.2007.63" @default.
• W2019932871 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18219299" @default.
• W2019932871 hasPublicationYear "2008" @default.
• W2019932871 type Work @default.
• W2019932871 sameAs 2019932871 @default.
• W2019932871 citedByCount "24" @default.
• W2019932871 countsByYear W20199328712013 @default.
• W2019932871 countsByYear W20199328712014 @default.
• W2019932871 countsByYear W20199328712015 @default.
• W2019932871 countsByYear W20199328712016 @default.
• W2019932871 countsByYear W20199328712017 @default.
• W2019932871 countsByYear W20199328712018 @default.
• W2019932871 countsByYear W20199328712020 @default.
• W2019932871 crossrefType "journal-article" @default.
• W2019932871 hasAuthorship W2019932871A5010367070 @default.
• W2019932871 hasAuthorship W2019932871A5024831837 @default.
• W2019932871 hasAuthorship W2019932871A5043270519 @default.
• W2019932871 hasAuthorship W2019932871A5057033238 @default.
• W2019932871 hasAuthorship W2019932871A5063227767 @default.
• W2019932871 hasBestOaLocation W20199328711 @default.
• W2019932871 hasConcept C126322002 @default.
• W2019932871 hasConcept C134018914 @default.
• W2019932871 hasConcept C138976137 @default.
• W2019932871 hasConcept C142225936 @default.
• W2019932871 hasConcept C159641895 @default.
• W2019932871 hasConcept C178790620 @default.
• W2019932871 hasConcept C178853913 @default.
• W2019932871 hasConcept C185592680 @default.
• W2019932871 hasConcept C198710026 @default.
• W2019932871 hasConcept C21652263 @default.
• W2019932871 hasConcept C27016395 @default.
• W2019932871 hasConcept C2775940317 @default.
• W2019932871 hasConcept C2776452961 @default.
• W2019932871 hasConcept C2777953023 @default.
• W2019932871 hasConcept C2778525890 @default.
• W2019932871 hasConcept C2780091579 @default.
• W2019932871 hasConcept C2781073237 @default.
• W2019932871 hasConcept C2908929049 @default.
• W2019932871 hasConcept C537181965 @default.
• W2019932871 hasConcept C71924100 @default.
• W2019932871 hasConcept C84393581 @default.
• W2019932871 hasConceptScore W2019932871C126322002 @default.
• W2019932871 hasConceptScore W2019932871C134018914 @default.
• W2019932871 hasConceptScore W2019932871C138976137 @default.
• W2019932871 hasConceptScore W2019932871C142225936 @default.
• W2019932871 hasConceptScore W2019932871C159641895 @default.
• W2019932871 hasConceptScore W2019932871C178790620 @default.
• W2019932871 hasConceptScore W2019932871C178853913 @default.
• W2019932871 hasConceptScore W2019932871C185592680 @default.
• W2019932871 hasConceptScore W2019932871C198710026 @default.
• W2019932871 hasConceptScore W2019932871C21652263 @default.
• W2019932871 hasConceptScore W2019932871C27016395 @default.
• W2019932871 hasConceptScore W2019932871C2775940317 @default.
• W2019932871 hasConceptScore W2019932871C2776452961 @default.
• W2019932871 hasConceptScore W2019932871C2777953023 @default.
• W2019932871 hasConceptScore W2019932871C2778525890 @default.
• W2019932871 hasConceptScore W2019932871C2780091579 @default.
• W2019932871 hasConceptScore W2019932871C2781073237 @default.
• W2019932871 hasConceptScore W2019932871C2908929049 @default.
• W2019932871 hasConceptScore W2019932871C537181965 @default.
• W2019932871 hasConceptScore W2019932871C71924100 @default.
• W2019932871 hasConceptScore W2019932871C84393581 @default.

• next