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- W2019933440 abstract "We present a novel centrifugal microfluidic platform for the highly efficient manipulation and analysis of particles for applications in bead-based assays. The platform uses an array of geometrical V-cup barriers to trap particles using stopped-flow sedimentation under highly reproducible hydrodynamic conditions. The impact parameters governing the occupancy distribution and capture efficiency of the arrayed traps are investigated. The unique, nearly 100% capture efficiency paired with the capability to establish sharply peaked, single occupancy distributions enables a novel, digital readout mode for color-multiplexed, particle-based assays with low-complexity instrumentation. The presented technology marks an essential step towards a versatile platform for the integration of bead- and cell-based biological assays." @default.
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- W2019933440 date "2012-01-01" @default.
- W2019933440 modified "2023-10-18" @default.
- W2019933440 title "Array-based capture, distribution, counting and multiplexed assaying of beads on a centrifugal microfluidic platform" @default.
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- W2019933440 doi "https://doi.org/10.1039/c2lc21170j" @default.
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