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• W2019934773 abstract "Herein, we report the development of two fluorescent probes for the highly selective and sensitive detection of H2S. The probes take advantage of a Cu(II)-cyclen complex, which acts as a reaction center for H2S and as a quencher of BODIPY (boron-dipyrromethene)-based fluorophores with emissions at 765 and 680 nm, respectively. These non-fluorescent probes could only be turned on by the addition of H2 S, and not by other potentially interfering biomolecules, including reactive oxygen species, cysteine, and glutathione. In a chemical system, both probes detected H2S with a detection limit of 80 nM. The probes were successfully used for the endogenous detection of H2S in HEK 293 cells, for measuring the H2S-release activity of dietary organosulfides in MCF-7 cells, and for the in vivo imaging of H2S in mice." @default.
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• W2019934773 date "2014-09-26" @default.
• W2019934773 modified "2023-09-30" @default.
• W2019934773 title "Highly Selective and Sensitive Near-Infrared-Fluorescent Probes for the Detection of Cellular Hydrogen Sulfide and the Imaging of H₂S in Mice" @default.
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• W2019934773 doi "https://doi.org/10.1002/asia.201402860" @default.
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