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- W2019938461 abstract "Vaginal bleeding and subchorionic hematomas are associated with increased risk of both early and late pregnancy loss. Previous work suggests that thrombin generation may play a pivotal role in development of these complications. Specifically, in human endometrial stromal cells (HESC), thrombin acts via protease-activated receptors (e.g. PAR-1) to induce matrix metalloproteinases (MMPs) and inflammatory factors. Our hypothesis is that thrombin activates MMPs and disrupts expression of genes involved in matrix homeostasis." @default.
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- W2019938461 date "2014-09-01" @default.
- W2019938461 modified "2023-10-16" @default.
- W2019938461 title "Thrombin alters decidualization and matrix homeostasis in human endometrial stromal cells" @default.
- W2019938461 doi "https://doi.org/10.1016/j.fertnstert.2014.07.808" @default.
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