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• W2019943197 abstract "The HCV IRES is a highly structured RNA which mediates cap-independent translation initiation in higher eukaryotes. This function is encoded in conserved structural motifs in the two major domains of HCV and HCV-like IRESs, which play crucial and distinct roles along the initiation pathway. In this review, I discuss structural features of IRES domains and how these RNA motifs function as RNA-based initiation factors to form 48S initiation complexes and 80S ribosomes with only a subset of canonical, protein-based eukaryotic initiation factors." @default.
• W2019943197 created "2016-06-24" @default.
• W2019943197 creator A5045260699 @default.
• W2019943197 date "2009-02-01" @default.
• W2019943197 modified "2023-09-30" @default.
• W2019943197 title "Structure and function of HCV IRES domains" @default.
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• W2019943197 doi "https://doi.org/10.1016/j.virusres.2008.06.004" @default.
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