FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019943993> ?p ?o ?g. }

• W2019943993 endingPage "227" @default.
• W2019943993 startingPage "217" @default.
• W2019943993 abstract "The present experiments were undertaken to study whether amygdala kindling induces persistent alterations in the functional status of neurons of the central piriform cortex, a subregion of the piriform cortex identified previously as a site involved in the kindling process. Extracellular, single-unit recordings of piriform cortex neurons were made in anesthetized fully kindled rats at an interval of at least five weeks after the last seizure. Electrode implanted but not kindled rats served as sham controls. An additional group of non-implanted rats was used as naive controls. Spontaneously firing piriform cortex neurons were characterized in all groups by smooth, sharp, biphasic (i.e. positive/negative) action potentials with a duration of 0.8-1.8 ms, and were primarily located at the border between piriform cortex layers II and III. In kindled rats, neurons in the central piriform cortex exhibited a significantly higher firing rate compared to controls. Based on median group values, the increase in basal activity in kindled rats averaged about 90%. The responsiveness of piriform cortex neurons to neurotransmitters was tested by microiontophoretic application of glutamate, N-methyl-D-aspartate and GABA. Piriform cortex neurons of kindled rats exhibited a significantly lower responsiveness to the excitatory effect of glutamate than naive controls. A lowered glutamate responsiveness was also seen in sham controls. No significantly altered transmitter sensitivities of piriform cortex neurons from kindled rats were seen with N-methyl-D-aspartate or GABA. The data indicate that amygdala kindling causes persistent interictal changes in both basal activity and glutamate responsiveness of central piriform cortex neurons which could contribute to the abnormal hyperexcitability characteristic of kindling." @default.
• W2019943993 created "2016-06-24" @default.
• W2019943993 creator A5010235451 @default.
• W2019943993 creator A5019293899 @default.
• W2019943993 creator A5055755177 @default.
• W2019943993 creator A5078172111 @default.
• W2019943993 date "2000-09-01" @default.
• W2019943993 modified "2023-10-17" @default.
• W2019943993 title "Kindling causes persistent in vivo changes in firing rates and glutamate sensitivity of central piriform cortex neurons in rats" @default.
• W2019943993 cites W1516336249 @default.
• W2019943993 cites W1609394567 @default.
• W2019943993 cites W1966416366 @default.
• W2019943993 cites W1969137145 @default.
• W2019943993 cites W1970514465 @default.
• W2019943993 cites W1972464320 @default.
• W2019943993 cites W1973426426 @default.
• W2019943993 cites W1974439800 @default.
• W2019943993 cites W1976378446 @default.
• W2019943993 cites W1978326730 @default.
• W2019943993 cites W1978582068 @default.
• W2019943993 cites W1987164395 @default.
• W2019943993 cites W1990680291 @default.
• W2019943993 cites W1991829536 @default.
• W2019943993 cites W1991857015 @default.
• W2019943993 cites W1992603366 @default.
• W2019943993 cites W1996191348 @default.
• W2019943993 cites W2000648733 @default.
• W2019943993 cites W2002608596 @default.
• W2019943993 cites W2003926011 @default.
• W2019943993 cites W2011615847 @default.
• W2019943993 cites W2028129200 @default.
• W2019943993 cites W2035626498 @default.
• W2019943993 cites W2037605538 @default.
• W2019943993 cites W2039236424 @default.
• W2019943993 cites W2043105055 @default.
• W2019943993 cites W2043756291 @default.
• W2019943993 cites W2046350676 @default.
• W2019943993 cites W2049381848 @default.
• W2019943993 cites W2056027060 @default.
• W2019943993 cites W2065917785 @default.
• W2019943993 cites W2069328624 @default.
• W2019943993 cites W2070094588 @default.
• W2019943993 cites W2070285245 @default.
• W2019943993 cites W2078725626 @default.
• W2019943993 cites W2087317214 @default.
• W2019943993 cites W2090624084 @default.
• W2019943993 cites W2091282229 @default.
• W2019943993 cites W2092874909 @default.
• W2019943993 cites W2095265949 @default.
• W2019943993 cites W2101041219 @default.
• W2019943993 cites W2103946141 @default.
• W2019943993 cites W2157543929 @default.
• W2019943993 cites W2414045371 @default.
• W2019943993 cites W38382617 @default.
• W2019943993 doi "https://doi.org/10.1016/s0306-4522(00)00195-0" @default.
• W2019943993 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10938427" @default.
• W2019943993 hasPublicationYear "2000" @default.
• W2019943993 type Work @default.
• W2019943993 sameAs 2019943993 @default.
• W2019943993 citedByCount "24" @default.
• W2019943993 countsByYear W20199439932014 @default.
• W2019943993 countsByYear W20199439932019 @default.
• W2019943993 countsByYear W20199439932020 @default.
• W2019943993 countsByYear W20199439932022 @default.
• W2019943993 crossrefType "journal-article" @default.
• W2019943993 hasAuthorship W2019943993A5010235451 @default.
• W2019943993 hasAuthorship W2019943993A5019293899 @default.
• W2019943993 hasAuthorship W2019943993A5055755177 @default.
• W2019943993 hasAuthorship W2019943993A5078172111 @default.
• W2019943993 hasConcept C100691959 @default.
• W2019943993 hasConcept C112592302 @default.
• W2019943993 hasConcept C126322002 @default.
• W2019943993 hasConcept C134018914 @default.
• W2019943993 hasConcept C169760540 @default.
• W2019943993 hasConcept C170493617 @default.
• W2019943993 hasConcept C17077164 @default.
• W2019943993 hasConcept C185592680 @default.
• W2019943993 hasConcept C24998067 @default.
• W2019943993 hasConcept C2777348757 @default.
• W2019943993 hasConcept C2779144063 @default.
• W2019943993 hasConcept C2780382662 @default.
• W2019943993 hasConcept C61174792 @default.
• W2019943993 hasConcept C71924100 @default.
• W2019943993 hasConcept C86803240 @default.
• W2019943993 hasConceptScore W2019943993C100691959 @default.
• W2019943993 hasConceptScore W2019943993C112592302 @default.
• W2019943993 hasConceptScore W2019943993C126322002 @default.
• W2019943993 hasConceptScore W2019943993C134018914 @default.
• W2019943993 hasConceptScore W2019943993C169760540 @default.
• W2019943993 hasConceptScore W2019943993C170493617 @default.
• W2019943993 hasConceptScore W2019943993C17077164 @default.
• W2019943993 hasConceptScore W2019943993C185592680 @default.
• W2019943993 hasConceptScore W2019943993C24998067 @default.
• W2019943993 hasConceptScore W2019943993C2777348757 @default.
• W2019943993 hasConceptScore W2019943993C2779144063 @default.
• W2019943993 hasConceptScore W2019943993C2780382662 @default.
• W2019943993 hasConceptScore W2019943993C61174792 @default.
• W2019943993 hasConceptScore W2019943993C71924100 @default.

• next