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• W2019944448 abstract "Cryoglobulinemic membranoproliferative glomerulonephritis, an extrahepatic manifestation of chronic hepatitis C virus infection, often poses a therapeutic challenge (1). Although glucocorticosteroids and interferon alpha are effective in controlling the acute phase of the disease, a sustained response is unusual after discontinuation of treatment (2,3). The combination of interferon alpha and ribavirin, a nucleoside analog with broad activity against both deoxyribonucleic acid and ribonucleic acid (RNA) viruses, may improve the prognosis of hepatitis C virus infection in patients without renal disease (4,5). The few studies of this combination in patients with hepatitis C virus–associated cryoglobulinemic glomerulonephritis have had variable results (6-8). We report two additional patients who achieved a long-term response with early combination antiviral treatment." @default.
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• W2019944448 date "2002-10-01" @default.
• W2019944448 modified "2023-10-17" @default.
• W2019944448 title "Interferon alpha and ribavirin for membranoproliferative glomerulonephritis and hepatitis C infection" @default.
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• W2019944448 doi "https://doi.org/10.1016/s0002-9343(02)01257-3" @default.
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