Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019948559> ?p ?o ?g. }
- W2019948559 endingPage "187" @default.
- W2019948559 startingPage "179" @default.
- W2019948559 abstract "Corticobasal degeneration (CBD) is a rare syndrome characterised by an asymmetrical rigidity with localised cortical signs, particularly apraxia. Using positron emission tomography, abnormal patterns of cortical metabolism have recently been shown. We have studied patterns of regional cerebral blood flow (rCBF) using single photon emission tomography, with the tracer 99Technetium hexamethylpropylenamine (HMPAO), in subjects with CBD. In subjects with CBD, compared with 12 age-matched normal controls, in the clinically more affected hemisphere a characteristic pattern was found with significant reductions in HMPAO uptake in the posterior frontal cortex (by 11.5%), and in the superior, inferior, anterior, and posterior parietal cortex (by 12.2, 12.9, 12.9, and 9.7, respectively). Reduced uptake was also found in the caudate (9.3%), putamen (9.7%), and thalamus (8.6%). In contrast, HMPAO uptake in the temporal and occipital cortex was normal. In comparison with 12 Parkinson's disease (PD) controls, significant reduced uptake was seen in the thalamus (9.0%), posterior frontal (8.9%), and inferior (9.9%), and anterior parietal (9.5%) cortex. A similar pattern of impaired uptake was seen in the clinically less/unaffected cerebral hemisphere in patients with CBD compared with normal controls, with a significant reduction in HMPAO uptake in the thalamus (6.8%), superior parietal (9.6%) and anterior parietal (7.6%), and posterior parietal (7.3%) cortex. This implies that the disease process is bilateral even in those cases with clinically unilateral disease. This widely available technique may be useful in the early diagnosis of CBD and in differentiation from other extrapyramidal disorders." @default.
- W2019948559 created "2016-06-24" @default.
- W2019948559 creator A5002796221 @default.
- W2019948559 creator A5003076929 @default.
- W2019948559 creator A5019569712 @default.
- W2019948559 creator A5056940847 @default.
- W2019948559 creator A5063335320 @default.
- W2019948559 date "1995-03-01" @default.
- W2019948559 modified "2023-10-16" @default.
- W2019948559 title "Patterns of regional cerebral blood flow in corticobasal degeneration studied using HMPAO SPECT; comparison with Parkinson's disease and normal controls" @default.
- W2019948559 cites W1984671881 @default.
- W2019948559 cites W1991740874 @default.
- W2019948559 cites W1999066011 @default.
- W2019948559 cites W2008560062 @default.
- W2019948559 cites W2014251174 @default.
- W2019948559 cites W2017897564 @default.
- W2019948559 cites W2029563504 @default.
- W2019948559 cites W2061398333 @default.
- W2019948559 cites W2064996887 @default.
- W2019948559 cites W2085269410 @default.
- W2019948559 cites W2105118669 @default.
- W2019948559 cites W2116429998 @default.
- W2019948559 cites W2135823866 @default.
- W2019948559 cites W2136554657 @default.
- W2019948559 cites W2148293199 @default.
- W2019948559 cites W4243799182 @default.
- W2019948559 doi "https://doi.org/10.1002/mds.870100208" @default.
- W2019948559 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7753060" @default.
- W2019948559 hasPublicationYear "1995" @default.
- W2019948559 type Work @default.
- W2019948559 sameAs 2019948559 @default.
- W2019948559 citedByCount "80" @default.
- W2019948559 countsByYear W20199485592012 @default.
- W2019948559 countsByYear W20199485592013 @default.
- W2019948559 countsByYear W20199485592014 @default.
- W2019948559 countsByYear W20199485592015 @default.
- W2019948559 countsByYear W20199485592016 @default.
- W2019948559 countsByYear W20199485592017 @default.
- W2019948559 countsByYear W20199485592018 @default.
- W2019948559 countsByYear W20199485592019 @default.
- W2019948559 countsByYear W20199485592021 @default.
- W2019948559 countsByYear W20199485592022 @default.
- W2019948559 crossrefType "journal-article" @default.
- W2019948559 hasAuthorship W2019948559A5002796221 @default.
- W2019948559 hasAuthorship W2019948559A5003076929 @default.
- W2019948559 hasAuthorship W2019948559A5019569712 @default.
- W2019948559 hasAuthorship W2019948559A5056940847 @default.
- W2019948559 hasAuthorship W2019948559A5063335320 @default.
- W2019948559 hasConcept C105702510 @default.
- W2019948559 hasConcept C142724271 @default.
- W2019948559 hasConcept C15744967 @default.
- W2019948559 hasConcept C157767197 @default.
- W2019948559 hasConcept C164705383 @default.
- W2019948559 hasConcept C169760540 @default.
- W2019948559 hasConcept C2776818353 @default.
- W2019948559 hasConcept C2776936178 @default.
- W2019948559 hasConcept C2777348757 @default.
- W2019948559 hasConcept C2779134260 @default.
- W2019948559 hasConcept C2779246727 @default.
- W2019948559 hasConcept C2779422653 @default.
- W2019948559 hasConcept C2779483572 @default.
- W2019948559 hasConcept C2779714222 @default.
- W2019948559 hasConcept C2781041448 @default.
- W2019948559 hasConcept C2781423529 @default.
- W2019948559 hasConcept C2993858690 @default.
- W2019948559 hasConcept C6757342 @default.
- W2019948559 hasConcept C71924100 @default.
- W2019948559 hasConceptScore W2019948559C105702510 @default.
- W2019948559 hasConceptScore W2019948559C142724271 @default.
- W2019948559 hasConceptScore W2019948559C15744967 @default.
- W2019948559 hasConceptScore W2019948559C157767197 @default.
- W2019948559 hasConceptScore W2019948559C164705383 @default.
- W2019948559 hasConceptScore W2019948559C169760540 @default.
- W2019948559 hasConceptScore W2019948559C2776818353 @default.
- W2019948559 hasConceptScore W2019948559C2776936178 @default.
- W2019948559 hasConceptScore W2019948559C2777348757 @default.
- W2019948559 hasConceptScore W2019948559C2779134260 @default.
- W2019948559 hasConceptScore W2019948559C2779246727 @default.
- W2019948559 hasConceptScore W2019948559C2779422653 @default.
- W2019948559 hasConceptScore W2019948559C2779483572 @default.
- W2019948559 hasConceptScore W2019948559C2779714222 @default.
- W2019948559 hasConceptScore W2019948559C2781041448 @default.
- W2019948559 hasConceptScore W2019948559C2781423529 @default.
- W2019948559 hasConceptScore W2019948559C2993858690 @default.
- W2019948559 hasConceptScore W2019948559C6757342 @default.
- W2019948559 hasConceptScore W2019948559C71924100 @default.
- W2019948559 hasIssue "2" @default.
- W2019948559 hasLocation W20199485591 @default.
- W2019948559 hasLocation W20199485592 @default.
- W2019948559 hasOpenAccess W2019948559 @default.
- W2019948559 hasPrimaryLocation W20199485591 @default.
- W2019948559 hasRelatedWork W122299016 @default.
- W2019948559 hasRelatedWork W1926002420 @default.
- W2019948559 hasRelatedWork W1996369062 @default.
- W2019948559 hasRelatedWork W2008402030 @default.
- W2019948559 hasRelatedWork W2019948559 @default.
- W2019948559 hasRelatedWork W2142927400 @default.
- W2019948559 hasRelatedWork W2327879816 @default.