Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019955021> ?p ?o ?g. }
- W2019955021 endingPage "113" @default.
- W2019955021 startingPage "101" @default.
- W2019955021 abstract "The Corynebacterium glutamicum genome codes for 7 sigma subunits (factors) of RNA polymerase (RNAP): primary sigma factor SigA (σ(A)), primary-like SigB and 5 other alternative sigma factors (SigC, SigD, SigE, SigH and SigM). Each sigma factor is responsible for recognizing promoters of genes belonging to a regulon (sigmulon) involved in specific functions of the cell. Most promoters of C. glutamicum housekeeping genes are recognized by RNAP+σ(A), whereas σ(B) is involved in transcription of a large group of genes active during the transition phase between the exponential and stationary growth phases when various stress factors threaten to damage the cell. The σ(H) regulon consists of the genes involved in heat shock response including those coding for regulators and other sigma factors. It seems therefore that σ(H) occupies a central position in the cross-regulated network of sigma factors and controls their concerted response to various stress conditions in C. glutamicum. The σ(M) factor was found to regulate genes responding to oxidative stress. The main role of σ(E) is to activate genes involved in response to a cell surface stress. Promoters of individual classes recognized by different sigma factors are compiled and the respective consensus sequences of their key recognition motifs (-35 and -10 regions) are derived. In a number of genes, two or more promoters controlled by the same or different sigma factors were discovered. These multiple, overlapping or dual promoters contribute to a complex gene transcription control mechanisms that integrate internal and external signals and tune gene expression in cells as required by environmental and physiological conditions." @default.
- W2019955021 created "2016-06-24" @default.
- W2019955021 creator A5024253665 @default.
- W2019955021 creator A5026900011 @default.
- W2019955021 date "2011-07-01" @default.
- W2019955021 modified "2023-10-18" @default.
- W2019955021 title "Sigma factors and promoters in Corynebacterium glutamicum" @default.
- W2019955021 cites W1501899261 @default.
- W2019955021 cites W1538019557 @default.
- W2019955021 cites W1555480847 @default.
- W2019955021 cites W1570902726 @default.
- W2019955021 cites W1607802369 @default.
- W2019955021 cites W1662595962 @default.
- W2019955021 cites W1672256570 @default.
- W2019955021 cites W1799809787 @default.
- W2019955021 cites W1862595424 @default.
- W2019955021 cites W1869589678 @default.
- W2019955021 cites W1917921565 @default.
- W2019955021 cites W1921558906 @default.
- W2019955021 cites W1960763608 @default.
- W2019955021 cites W1966204475 @default.
- W2019955021 cites W1969006483 @default.
- W2019955021 cites W1976861576 @default.
- W2019955021 cites W1979836544 @default.
- W2019955021 cites W1980312009 @default.
- W2019955021 cites W1984471428 @default.
- W2019955021 cites W1987620868 @default.
- W2019955021 cites W1988525433 @default.
- W2019955021 cites W1995069545 @default.
- W2019955021 cites W2000425923 @default.
- W2019955021 cites W2002457199 @default.
- W2019955021 cites W2005221052 @default.
- W2019955021 cites W2005522635 @default.
- W2019955021 cites W2005918853 @default.
- W2019955021 cites W2009663387 @default.
- W2019955021 cites W2012550217 @default.
- W2019955021 cites W2013360743 @default.
- W2019955021 cites W2018342225 @default.
- W2019955021 cites W2021511385 @default.
- W2019955021 cites W2024055037 @default.
- W2019955021 cites W2029349945 @default.
- W2019955021 cites W2030491754 @default.
- W2019955021 cites W2030937324 @default.
- W2019955021 cites W2035020289 @default.
- W2019955021 cites W2037728701 @default.
- W2019955021 cites W2038613897 @default.
- W2019955021 cites W2040085356 @default.
- W2019955021 cites W2048860208 @default.
- W2019955021 cites W2051048419 @default.
- W2019955021 cites W2059432107 @default.
- W2019955021 cites W2063371204 @default.
- W2019955021 cites W2067563413 @default.
- W2019955021 cites W2073827015 @default.
- W2019955021 cites W2075321830 @default.
- W2019955021 cites W2078124126 @default.
- W2019955021 cites W2087123846 @default.
- W2019955021 cites W2091052813 @default.
- W2019955021 cites W2096376234 @default.
- W2019955021 cites W2096606273 @default.
- W2019955021 cites W2097131018 @default.
- W2019955021 cites W2099930370 @default.
- W2019955021 cites W2100941430 @default.
- W2019955021 cites W2102730721 @default.
- W2019955021 cites W2104057607 @default.
- W2019955021 cites W2106389458 @default.
- W2019955021 cites W2106794069 @default.
- W2019955021 cites W2107443178 @default.
- W2019955021 cites W2107743714 @default.
- W2019955021 cites W2110694729 @default.
- W2019955021 cites W2111221302 @default.
- W2019955021 cites W2111293582 @default.
- W2019955021 cites W2115741455 @default.
- W2019955021 cites W2117549113 @default.
- W2019955021 cites W2123697930 @default.
- W2019955021 cites W2126757950 @default.
- W2019955021 cites W2127145948 @default.
- W2019955021 cites W2130974340 @default.
- W2019955021 cites W2133781129 @default.
- W2019955021 cites W2134418747 @default.
- W2019955021 cites W2137253734 @default.
- W2019955021 cites W2137380242 @default.
- W2019955021 cites W2137802183 @default.
- W2019955021 cites W2138532285 @default.
- W2019955021 cites W2139333971 @default.
- W2019955021 cites W2141454736 @default.
- W2019955021 cites W2142776290 @default.
- W2019955021 cites W2143521363 @default.
- W2019955021 cites W2143984655 @default.
- W2019955021 cites W2144214902 @default.
- W2019955021 cites W2145111771 @default.
- W2019955021 cites W2146569474 @default.
- W2019955021 cites W2147057508 @default.
- W2019955021 cites W2147647191 @default.
- W2019955021 cites W2148243489 @default.
- W2019955021 cites W2148749184 @default.
- W2019955021 cites W2149146891 @default.
- W2019955021 cites W2149418298 @default.
- W2019955021 cites W2150717139 @default.