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- W2019956501 abstract "Patients that receive coronary bare-metal or drug-eluting stents have to be maintained on dual antiplatelet therapy (DAPT) for at least 4 weeks or 12 months, respectively. The prolonged time period required for drug-eluting stents is the result of delayed vascular healing that is associated with the drug and the polymeric coating. Premature cessation of DAPT may precipitate life-threatening stent thrombosis. However, some urgent, unplanned surgical procedures cannot be carried out under DAPT as a result of an unacceptable bleeding risk. Therefore, in these particular patients, DAPT therapy needs to be bridged for urgent surgery to avoid stent thrombosis, yet no clinical recommendation about a specific pharmacologic protocol is currently available for this specific purpose. We report about the initial experience with a novel institutional bridging protocol using bivalirudin that has been developed and applied successfully in a limited number of patients." @default.
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- W2019956501 date "2011-11-01" @default.
- W2019956501 modified "2023-09-25" @default.
- W2019956501 title "Initial Experience With an Institutional Bridging Protocol for Patients With Recent Coronary Stent Implantation Requiring Discontinuation of Dual Antiplatelet Therapy Resulting From Urgent Surgery" @default.
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- W2019956501 doi "https://doi.org/10.1097/mjt.0b013e3181df8e31" @default.
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