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- W2019966453 abstract "Emilio Perucca and colleagues discuss the design of SANAD. SANAD was not blinded and collection of blinded long-term data was not possible. A shorter blinded trial might have been feasible, but would not have recruited such a large cohort, nor examined the longer term outcomes that are so important in chronic diseases such as epilepsy. One of the primary outcomes, time to treatment failure, is an important outcome because it represents the trade-off between efficacy and tolerability, but it requires judgment and might have been affected by the lack of blinding." @default.
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- W2019966453 date "2007-07-01" @default.
- W2019966453 modified "2023-10-16" @default.
- W2019966453 title "Old versus new antiepileptic drugs: the SANAD study – Authors' reply" @default.
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- W2019966453 doi "https://doi.org/10.1016/s0140-6736(07)61154-4" @default.
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