FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019966970> ?p ?o ?g. }

• W2019966970 endingPage "740" @default.
• W2019966970 startingPage "733" @default.
• W2019966970 abstract "Partial sequence comparisons have recently indicated that two extracellular components, fibulin from human placenta and BM‐90 from a basement‐membrane‐producing mouse tumor, are either identical or closely related proteins. In this study, a complete sequence analysis of mouse BM‐90 cDNA showed a 539‐residue N‐terminal core structure (domains I and II), which was 85% identical with the same core structure of human fibulin. A 137‐residue C‐terminal sequence (domain III) was unique for BM‐90 and could also be identified by Edman degradation. This suggested a novel splice product, variant D, which is characteristic for the mouse tumor. A second 117‐residue C‐terminal sequence (domain III) was identified in additional mouse cDNA clones and showed 91% identity with the region specific for variant C of fibulin. Northern blots using mouse cells demonstrated two mRNA species, 2.7 kb and 2.3 kb, which encoded the variants D and C, respectively. The sequence of BM‐90/fibulin indicates the presence of nine epidermal‐growth‐factor‐like repeats in the core domain‐II structure, eight of which contain consensus motifs for calcium binding. This binding is apparently important for the interaction of BM‐90 with laminin and nidogen and for some weaker interactions with collagen IV. Further binding of BM‐90 was demonstrated to fibronectin and BM‐90 itself, but did not depend on calcium. Major binding sites for BM‐90 were identified at a C‐terminal segment of laminin A chain and at the N‐terminus of nidogen. The broad interaction repertoire of BM‐90 is comparable to that of nidogen and both proteins may have similar roles as connecting elements in the extracellular matrix." @default.
• W2019966970 created "2016-06-24" @default.
• W2019966970 creator A5003840254 @default.
• W2019966970 creator A5010047296 @default.
• W2019966970 creator A5056787953 @default.
• W2019966970 creator A5062918903 @default.
• W2019966970 creator A5076088995 @default.
• W2019966970 creator A5078385571 @default.
• W2019966970 date "1993-08-01" @default.
• W2019966970 modified "2023-10-13" @default.
• W2019966970 title "Sequence of extracellular mouse protein BM-90/fibulin and its calcium-dependent binding to other basement-membrane ligands" @default.
• W2019966970 cites W137168614 @default.
• W2019966970 cites W1561047920 @default.
• W2019966970 cites W1565263903 @default.
• W2019966970 cites W16659746 @default.
• W2019966970 cites W1869006121 @default.
• W2019966970 cites W1971156818 @default.
• W2019966970 cites W1984505687 @default.
• W2019966970 cites W1994634008 @default.
• W2019966970 cites W2005165360 @default.
• W2019966970 cites W2006140887 @default.
• W2019966970 cites W2012617112 @default.
• W2019966970 cites W2016085918 @default.
• W2019966970 cites W2030145963 @default.
• W2019966970 cites W2031070504 @default.
• W2019966970 cites W2040089477 @default.
• W2019966970 cites W2041754265 @default.
• W2019966970 cites W2041785424 @default.
• W2019966970 cites W2051811193 @default.
• W2019966970 cites W2055018696 @default.
• W2019966970 cites W2057862455 @default.
• W2019966970 cites W2058973638 @default.
• W2019966970 cites W2059505915 @default.
• W2019966970 cites W2061448045 @default.
• W2019966970 cites W2083715055 @default.
• W2019966970 cites W2088854697 @default.
• W2019966970 cites W2107312689 @default.
• W2019966970 cites W2118305149 @default.
• W2019966970 cites W2128647672 @default.
• W2019966970 cites W2138270253 @default.
• W2019966970 cites W2139421867 @default.
• W2019966970 cites W2155619649 @default.
• W2019966970 cites W2174272589 @default.
• W2019966970 cites W2212959237 @default.
• W2019966970 cites W2332263596 @default.
• W2019966970 cites W4294216491 @default.
• W2019966970 cites W941625536 @default.
• W2019966970 doi "https://doi.org/10.1111/j.1432-1033.1993.tb18086.x" @default.
• W2019966970 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8354280" @default.
• W2019966970 hasPublicationYear "1993" @default.
• W2019966970 type Work @default.
• W2019966970 sameAs 2019966970 @default.
• W2019966970 citedByCount "100" @default.
• W2019966970 countsByYear W20199669702012 @default.
• W2019966970 countsByYear W20199669702013 @default.
• W2019966970 countsByYear W20199669702014 @default.
• W2019966970 countsByYear W20199669702015 @default.
• W2019966970 countsByYear W20199669702017 @default.
• W2019966970 countsByYear W20199669702020 @default.
• W2019966970 crossrefType "journal-article" @default.
• W2019966970 hasAuthorship W2019966970A5003840254 @default.
• W2019966970 hasAuthorship W2019966970A5010047296 @default.
• W2019966970 hasAuthorship W2019966970A5056787953 @default.
• W2019966970 hasAuthorship W2019966970A5062918903 @default.
• W2019966970 hasAuthorship W2019966970A5076088995 @default.
• W2019966970 hasAuthorship W2019966970A5078385571 @default.
• W2019966970 hasBestOaLocation W20199669701 @default.
• W2019966970 hasConcept C104317684 @default.
• W2019966970 hasConcept C107824862 @default.
• W2019966970 hasConcept C153911025 @default.
• W2019966970 hasConcept C167625842 @default.
• W2019966970 hasConcept C185592680 @default.
• W2019966970 hasConcept C187882448 @default.
• W2019966970 hasConcept C189165786 @default.
• W2019966970 hasConcept C2776193487 @default.
• W2019966970 hasConcept C2778122751 @default.
• W2019966970 hasConcept C2779814568 @default.
• W2019966970 hasConcept C28406088 @default.
• W2019966970 hasConcept C552990157 @default.
• W2019966970 hasConcept C55493867 @default.
• W2019966970 hasConcept C61053724 @default.
• W2019966970 hasConcept C86492073 @default.
• W2019966970 hasConcept C86803240 @default.
• W2019966970 hasConcept C95444343 @default.
• W2019966970 hasConceptScore W2019966970C104317684 @default.
• W2019966970 hasConceptScore W2019966970C107824862 @default.
• W2019966970 hasConceptScore W2019966970C153911025 @default.
• W2019966970 hasConceptScore W2019966970C167625842 @default.
• W2019966970 hasConceptScore W2019966970C185592680 @default.
• W2019966970 hasConceptScore W2019966970C187882448 @default.
• W2019966970 hasConceptScore W2019966970C189165786 @default.
• W2019966970 hasConceptScore W2019966970C2776193487 @default.
• W2019966970 hasConceptScore W2019966970C2778122751 @default.
• W2019966970 hasConceptScore W2019966970C2779814568 @default.
• W2019966970 hasConceptScore W2019966970C28406088 @default.
• W2019966970 hasConceptScore W2019966970C552990157 @default.
• W2019966970 hasConceptScore W2019966970C55493867 @default.
• W2019966970 hasConceptScore W2019966970C61053724 @default.

• next