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- W2019967230 abstract "We tested noreleagnine, a beta-carboline which unlike other beta-carbolines remains in aqueous solution at physiological pH, as well as chlordiazepoxide, a traditional benzodiazepine, and their interaction with the benzodiazepine receptor antagonist R0 15-1788 in a modified approach schedule with two levels of conflict. Noreleagnine displayed pro-conflict activity characteristic of beta-carbolines and chlordiazepoxide elicited an anti-conflict effect, both of which were blocked by pretreatment with R0 15-1788. We believe this to be the first clear demonstration that noreleagnine has an anxiogenic effect and that this effect is mediated by its action on benzodiazepine receptors." @default.
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- W2019967230 date "1989-05-01" @default.
- W2019967230 modified "2023-10-16" @default.
- W2019967230 title "Anxiogenic effects of noreleagnine a water soluble beta-carboline in rats" @default.
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- W2019967230 doi "https://doi.org/10.1016/0028-3908(89)90092-0" @default.
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