FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019967763> ?p ?o ?g. }

• W2019967763 endingPage "849" @default.
• W2019967763 startingPage "846" @default.
• W2019967763 abstract "The aim of this study was to determine the maximum tolerated dose of a fixed dose of docetaxel when combined with continuous infusion ifosfamide, with and without G-CSF support, in the treatment of advanced cancer, and to evaluate anti-tumour activity of this combination. Thirty-one patients with advanced malignancies were treated with docetaxel 75 mg/m(2) intravenously on days 1, and ifosfamide at increasing dose levels from 1500 mg/m(2)/day to 2750 mg/m(2)/day as a continuous infusion from day 1-3, every 3 weeks. A total of 107 cycles of treatment were administered. Without G-CSF support dose-limiting toxicity of grade 4 neutropenia greater than 5 days duration occurred at dose level 1. With the addition of G-CSF the maximum tolerated dose was docetaxel 75 mg/m(2) on day 1 and ifosfamide 2750 mg/m(2)/day on days 1-3. Dose limiting toxicity (DLT) included ifosfamide-induced encephalopathy, febrile neutropenia and grade three mucositis. Three complete responses and 3 partial responses were seen. This combination of docetaxel and infusional ifosfamide is feasible and effective. The recommended dose for future phase II studies is docetaxel 75 mg/m(2) on day 1 and ifosfamide 2500 mg/m(2)/day continuous infusion on days 1-3." @default.
• W2019967763 created "2016-06-24" @default.
• W2019967763 creator A5004162577 @default.
• W2019967763 creator A5045684532 @default.
• W2019967763 creator A5046335734 @default.
• W2019967763 creator A5085249986 @default.
• W2019967763 creator A5090145105 @default.
• W2019967763 date "2002-10-01" @default.
• W2019967763 modified "2023-10-07" @default.
• W2019967763 title "Phase I study of docetaxel plus ifosfamide in patients with advanced cancer" @default.
• W2019967763 cites W1512107609 @default.
• W2019967763 cites W1834370350 @default.
• W2019967763 cites W1835575651 @default.
• W2019967763 cites W1846747462 @default.
• W2019967763 cites W1949811104 @default.
• W2019967763 cites W1959506700 @default.
• W2019967763 cites W1996370342 @default.
• W2019967763 cites W2030404564 @default.
• W2019967763 cites W2031600030 @default.
• W2019967763 cites W2076932287 @default.
• W2019967763 cites W2077084156 @default.
• W2019967763 cites W2084390110 @default.
• W2019967763 cites W2086909567 @default.
• W2019967763 cites W2088226803 @default.
• W2019967763 cites W2121247384 @default.
• W2019967763 cites W2130652363 @default.
• W2019967763 cites W2138550636 @default.
• W2019967763 cites W2138734774 @default.
• W2019967763 cites W2167805334 @default.
• W2019967763 cites W2170346929 @default.
• W2019967763 cites W2473298943 @default.
• W2019967763 cites W4233358210 @default.
• W2019967763 doi "https://doi.org/10.1038/sj.bjc.6600542" @default.
• W2019967763 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2376167" @default.
• W2019967763 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12373597" @default.
• W2019967763 hasPublicationYear "2002" @default.
• W2019967763 type Work @default.
• W2019967763 sameAs 2019967763 @default.
• W2019967763 citedByCount "3" @default.
• W2019967763 crossrefType "journal-article" @default.
• W2019967763 hasAuthorship W2019967763A5004162577 @default.
• W2019967763 hasAuthorship W2019967763A5045684532 @default.
• W2019967763 hasAuthorship W2019967763A5046335734 @default.
• W2019967763 hasAuthorship W2019967763A5085249986 @default.
• W2019967763 hasAuthorship W2019967763A5090145105 @default.
• W2019967763 hasBestOaLocation W20199677631 @default.
• W2019967763 hasConcept C121608353 @default.
• W2019967763 hasConcept C126322002 @default.
• W2019967763 hasConcept C126894567 @default.
• W2019967763 hasConcept C141071460 @default.
• W2019967763 hasConcept C2776694085 @default.
• W2019967763 hasConcept C2776755627 @default.
• W2019967763 hasConcept C2777063308 @default.
• W2019967763 hasConcept C2777506904 @default.
• W2019967763 hasConcept C2777899217 @default.
• W2019967763 hasConcept C2778239845 @default.
• W2019967763 hasConcept C2778496288 @default.
• W2019967763 hasConcept C2778670039 @default.
• W2019967763 hasConcept C2778850193 @default.
• W2019967763 hasConcept C2778971682 @default.
• W2019967763 hasConcept C2780192828 @default.
• W2019967763 hasConcept C2781190966 @default.
• W2019967763 hasConcept C29730261 @default.
• W2019967763 hasConcept C42219234 @default.
• W2019967763 hasConcept C71924100 @default.
• W2019967763 hasConcept C90924648 @default.
• W2019967763 hasConceptScore W2019967763C121608353 @default.
• W2019967763 hasConceptScore W2019967763C126322002 @default.
• W2019967763 hasConceptScore W2019967763C126894567 @default.
• W2019967763 hasConceptScore W2019967763C141071460 @default.
• W2019967763 hasConceptScore W2019967763C2776694085 @default.
• W2019967763 hasConceptScore W2019967763C2776755627 @default.
• W2019967763 hasConceptScore W2019967763C2777063308 @default.
• W2019967763 hasConceptScore W2019967763C2777506904 @default.
• W2019967763 hasConceptScore W2019967763C2777899217 @default.
• W2019967763 hasConceptScore W2019967763C2778239845 @default.
• W2019967763 hasConceptScore W2019967763C2778496288 @default.
• W2019967763 hasConceptScore W2019967763C2778670039 @default.
• W2019967763 hasConceptScore W2019967763C2778850193 @default.
• W2019967763 hasConceptScore W2019967763C2778971682 @default.
• W2019967763 hasConceptScore W2019967763C2780192828 @default.
• W2019967763 hasConceptScore W2019967763C2781190966 @default.
• W2019967763 hasConceptScore W2019967763C29730261 @default.
• W2019967763 hasConceptScore W2019967763C42219234 @default.
• W2019967763 hasConceptScore W2019967763C71924100 @default.
• W2019967763 hasConceptScore W2019967763C90924648 @default.
• W2019967763 hasIssue "8" @default.
• W2019967763 hasLocation W20199677631 @default.
• W2019967763 hasLocation W20199677632 @default.
• W2019967763 hasLocation W20199677633 @default.
• W2019967763 hasLocation W20199677634 @default.
• W2019967763 hasOpenAccess W2019967763 @default.
• W2019967763 hasPrimaryLocation W20199677631 @default.
• W2019967763 hasRelatedWork W2019967763 @default.
• W2019967763 hasRelatedWork W2042513738 @default.
• W2019967763 hasRelatedWork W2084246274 @default.
• W2019967763 hasRelatedWork W2086412457 @default.
• W2019967763 hasRelatedWork W2086909567 @default.

• next