FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019967799> ?p ?o ?g. }

• W2019967799 endingPage "608" @default.
• W2019967799 startingPage "600" @default.
• W2019967799 abstract "Objectives. To assess the efficacy, tolerability, and safety of NGX-4010, a high-concentration capsaicin dermal patch (capsaicin 640 μg/cm2, 8%) in patients with postherpetic neuralgia (PHN). Methods. Patients were randomized to receive NGX-4010 or control patch in a 4-week, double-blind study. This was followed by an open-label extension phase (up to 48 weeks total) where patients could receive up to three additional treatments no sooner than 12 weeks after initial treatment. The primary efficacy variable was mean change from baseline in mean morning and evening numerical pain rating scale (NPRS) scores. Results. During days 8–28 after the double-blind treatment, NGX-4010 patients had a mean change in NPRS scores from baseline of −32.7% compared with −4.4% for control patients (P = 0.003). Mean NPRS scores decreased from baseline during week 1 in both treatment groups, remained relatively stable through week 12 in NXG-4010 patients, but returned to near baseline during weeks 2–4 in controls. Mean change in NPRS scores from baseline during weeks 2–12 was −33.8% for NGX-4010 and +4.9% for control recipients. A similar decrease in NPRS scores from baseline was maintained with subsequent NGX-4010 treatments, regardless of the number of treatments received. Transient increases in application site pain were adequately managed with analgesics. No increases in application site reactions or adverse events were observed with repeated treatments. No patients discontinued the study due to an adverse event. Conclusion. NGX-4010 is a promising topical treatment for PHN patients, which appears to be tolerable, generally safe, and effective." @default.
• W2019967799 created "2016-06-24" @default.
• W2019967799 creator A5005895696 @default.
• W2019967799 creator A5016650592 @default.
• W2019967799 creator A5082943129 @default.
• W2019967799 creator A5086554116 @default.
• W2019967799 date "2010-04-01" @default.
• W2019967799 modified "2023-09-23" @default.
• W2019967799 title "NGX-4010, a High-Concentration Capsaicin Patch, for the Treatment of Postherpetic Neuralgia: A Randomized, Double-Blind, Controlled Study with an Open-Label Extension" @default.
• W2019967799 cites W1971005199 @default.
• W2019967799 cites W1971020268 @default.
• W2019967799 cites W2000102513 @default.
• W2019967799 cites W2018652055 @default.
• W2019967799 cites W2027814779 @default.
• W2019967799 cites W2028934683 @default.
• W2019967799 cites W2030094128 @default.
• W2019967799 cites W2058917612 @default.
• W2019967799 cites W2067568481 @default.
• W2019967799 cites W2074624136 @default.
• W2019967799 cites W2094310013 @default.
• W2019967799 cites W2094549307 @default.
• W2019967799 cites W2121270079 @default.
• W2019967799 cites W2124146642 @default.
• W2019967799 cites W2132309748 @default.
• W2019967799 cites W2161293372 @default.
• W2019967799 cites W2161563980 @default.
• W2019967799 cites W2166945641 @default.
• W2019967799 cites W2329242769 @default.
• W2019967799 cites W2333954443 @default.
• W2019967799 cites W4319308403 @default.
• W2019967799 doi "https://doi.org/10.1111/j.1526-4637.2009.00793.x" @default.
• W2019967799 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20113411" @default.
• W2019967799 hasPublicationYear "2010" @default.
• W2019967799 type Work @default.
• W2019967799 sameAs 2019967799 @default.
• W2019967799 citedByCount "137" @default.
• W2019967799 countsByYear W20199677992012 @default.
• W2019967799 countsByYear W20199677992013 @default.
• W2019967799 countsByYear W20199677992014 @default.
• W2019967799 countsByYear W20199677992015 @default.
• W2019967799 countsByYear W20199677992016 @default.
• W2019967799 countsByYear W20199677992017 @default.
• W2019967799 countsByYear W20199677992018 @default.
• W2019967799 countsByYear W20199677992019 @default.
• W2019967799 countsByYear W20199677992020 @default.
• W2019967799 countsByYear W20199677992021 @default.
• W2019967799 countsByYear W20199677992022 @default.
• W2019967799 crossrefType "journal-article" @default.
• W2019967799 hasAuthorship W2019967799A5005895696 @default.
• W2019967799 hasAuthorship W2019967799A5016650592 @default.
• W2019967799 hasAuthorship W2019967799A5082943129 @default.
• W2019967799 hasAuthorship W2019967799A5086554116 @default.
• W2019967799 hasBestOaLocation W20199677991 @default.
• W2019967799 hasConcept C121332964 @default.
• W2019967799 hasConcept C126322002 @default.
• W2019967799 hasConcept C1276947 @default.
• W2019967799 hasConcept C142724271 @default.
• W2019967799 hasConcept C168563851 @default.
• W2019967799 hasConcept C170493617 @default.
• W2019967799 hasConcept C19720800 @default.
• W2019967799 hasConcept C197934379 @default.
• W2019967799 hasConcept C204787440 @default.
• W2019967799 hasConcept C27081682 @default.
• W2019967799 hasConcept C2776476923 @default.
• W2019967799 hasConcept C2777107010 @default.
• W2019967799 hasConcept C2778375690 @default.
• W2019967799 hasConcept C2778866549 @default.
• W2019967799 hasConcept C2780016216 @default.
• W2019967799 hasConcept C2780051329 @default.
• W2019967799 hasConcept C2991744798 @default.
• W2019967799 hasConcept C42219234 @default.
• W2019967799 hasConcept C71924100 @default.
• W2019967799 hasConceptScore W2019967799C121332964 @default.
• W2019967799 hasConceptScore W2019967799C126322002 @default.
• W2019967799 hasConceptScore W2019967799C1276947 @default.
• W2019967799 hasConceptScore W2019967799C142724271 @default.
• W2019967799 hasConceptScore W2019967799C168563851 @default.
• W2019967799 hasConceptScore W2019967799C170493617 @default.
• W2019967799 hasConceptScore W2019967799C19720800 @default.
• W2019967799 hasConceptScore W2019967799C197934379 @default.
• W2019967799 hasConceptScore W2019967799C204787440 @default.
• W2019967799 hasConceptScore W2019967799C27081682 @default.
• W2019967799 hasConceptScore W2019967799C2776476923 @default.
• W2019967799 hasConceptScore W2019967799C2777107010 @default.
• W2019967799 hasConceptScore W2019967799C2778375690 @default.
• W2019967799 hasConceptScore W2019967799C2778866549 @default.
• W2019967799 hasConceptScore W2019967799C2780016216 @default.
• W2019967799 hasConceptScore W2019967799C2780051329 @default.
• W2019967799 hasConceptScore W2019967799C2991744798 @default.
• W2019967799 hasConceptScore W2019967799C42219234 @default.
• W2019967799 hasConceptScore W2019967799C71924100 @default.
• W2019967799 hasIssue "4" @default.
• W2019967799 hasLocation W20199677991 @default.
• W2019967799 hasLocation W20199677992 @default.
• W2019967799 hasOpenAccess W2019967799 @default.
• W2019967799 hasPrimaryLocation W20199677991 @default.
• W2019967799 hasRelatedWork W114379940 @default.
• W2019967799 hasRelatedWork W1513335853 @default.

• next