FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019968440> ?p ?o ?g. }

• W2019968440 endingPage "2371" @default.
• W2019968440 startingPage "2365" @default.
• W2019968440 abstract "We report a new, mass spectrometry-based method for measuring affinity constants for specific metal ion binding to DNA, particularly for quadruplex DNA. This method, which is applicable to other systems, utilizes the gas-phase signal fractions, as determined by mass spectrometry, from the bound and unbound species as input into a mathematical model that determines various parameters, one of which is the binding affinity constant. The system used to develop and test the model was the thrombin-binding aptamer, an appropriate quadruplex structure that binds both K+ and Sr2+ cations. Using this method, we measured the binding constants of potassium and strontium cations with the quadruplex structure to be 5000 and 240 nM, respectively. We then applied the method to measure the change in enthalpy of the binding of strontium cations to the thrombin binding aptamer. The ΔH for this interaction is −71 kJ/mol (−17 kcal/mol). The binding constant measurements are consistent with earlier measurements on the same system, and the measured change in enthalpy is in excellent agreement with previous work." @default.
• W2019968440 created "2016-06-24" @default.
• W2019968440 creator A5031479644 @default.
• W2019968440 creator A5061590980 @default.
• W2019968440 creator A5076508053 @default.
• W2019968440 date "2008-03-05" @default.
• W2019968440 modified "2023-10-11" @default.
• W2019968440 title "Method of Measuring Oligonucleotide−Metal Affinities: Interactions of the Thrombin Binding Aptamer with K⁺ and Sr²⁺" @default.
• W2019968440 cites W1552647544 @default.
• W2019968440 cites W1739424779 @default.
• W2019968440 cites W1980235240 @default.
• W2019968440 cites W1983023891 @default.
• W2019968440 cites W1985079632 @default.
• W2019968440 cites W1996497565 @default.
• W2019968440 cites W2009587501 @default.
• W2019968440 cites W2015321890 @default.
• W2019968440 cites W2021003022 @default.
• W2019968440 cites W2021856126 @default.
• W2019968440 cites W2028592651 @default.
• W2019968440 cites W2039658297 @default.
• W2019968440 cites W2045568382 @default.
• W2019968440 cites W2049909598 @default.
• W2019968440 cites W2051483365 @default.
• W2019968440 cites W2059305343 @default.
• W2019968440 cites W2081222587 @default.
• W2019968440 cites W2089816928 @default.
• W2019968440 cites W2091876286 @default.
• W2019968440 cites W2146799043 @default.
• W2019968440 cites W2150414812 @default.
• W2019968440 cites W2166976426 @default.
• W2019968440 cites W2171830519 @default.
• W2019968440 cites W2327237234 @default.
• W2019968440 cites W4230542440 @default.
• W2019968440 doi "https://doi.org/10.1021/ac701903w" @default.
• W2019968440 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18318508" @default.
• W2019968440 hasPublicationYear "2008" @default.
• W2019968440 type Work @default.
• W2019968440 sameAs 2019968440 @default.
• W2019968440 citedByCount "44" @default.
• W2019968440 countsByYear W20199684402012 @default.
• W2019968440 countsByYear W20199684402013 @default.
• W2019968440 countsByYear W20199684402014 @default.
• W2019968440 countsByYear W20199684402015 @default.
• W2019968440 countsByYear W20199684402016 @default.
• W2019968440 countsByYear W20199684402017 @default.
• W2019968440 countsByYear W20199684402020 @default.
• W2019968440 countsByYear W20199684402021 @default.
• W2019968440 countsByYear W20199684402022 @default.
• W2019968440 countsByYear W20199684402023 @default.
• W2019968440 crossrefType "journal-article" @default.
• W2019968440 hasAuthorship W2019968440A5031479644 @default.
• W2019968440 hasAuthorship W2019968440A5061590980 @default.
• W2019968440 hasAuthorship W2019968440A5076508053 @default.
• W2019968440 hasConcept C10710636 @default.
• W2019968440 hasConcept C107824862 @default.
• W2019968440 hasConcept C113196181 @default.
• W2019968440 hasConcept C121332964 @default.
• W2019968440 hasConcept C128972844 @default.
• W2019968440 hasConcept C145148216 @default.
• W2019968440 hasConcept C147789679 @default.
• W2019968440 hasConcept C162356407 @default.
• W2019968440 hasConcept C168191866 @default.
• W2019968440 hasConcept C178790620 @default.
• W2019968440 hasConcept C185544564 @default.
• W2019968440 hasConcept C185592680 @default.
• W2019968440 hasConcept C2780283098 @default.
• W2019968440 hasConcept C32786932 @default.
• W2019968440 hasConcept C3288061 @default.
• W2019968440 hasConcept C43617362 @default.
• W2019968440 hasConcept C518915863 @default.
• W2019968440 hasConcept C54355233 @default.
• W2019968440 hasConcept C544153396 @default.
• W2019968440 hasConcept C55493867 @default.
• W2019968440 hasConcept C71240020 @default.
• W2019968440 hasConcept C86803240 @default.
• W2019968440 hasConcept C93282013 @default.
• W2019968440 hasConcept C97355855 @default.
• W2019968440 hasConceptScore W2019968440C10710636 @default.
• W2019968440 hasConceptScore W2019968440C107824862 @default.
• W2019968440 hasConceptScore W2019968440C113196181 @default.
• W2019968440 hasConceptScore W2019968440C121332964 @default.
• W2019968440 hasConceptScore W2019968440C128972844 @default.
• W2019968440 hasConceptScore W2019968440C145148216 @default.
• W2019968440 hasConceptScore W2019968440C147789679 @default.
• W2019968440 hasConceptScore W2019968440C162356407 @default.
• W2019968440 hasConceptScore W2019968440C168191866 @default.
• W2019968440 hasConceptScore W2019968440C178790620 @default.
• W2019968440 hasConceptScore W2019968440C185544564 @default.
• W2019968440 hasConceptScore W2019968440C185592680 @default.
• W2019968440 hasConceptScore W2019968440C2780283098 @default.
• W2019968440 hasConceptScore W2019968440C32786932 @default.
• W2019968440 hasConceptScore W2019968440C3288061 @default.
• W2019968440 hasConceptScore W2019968440C43617362 @default.
• W2019968440 hasConceptScore W2019968440C518915863 @default.
• W2019968440 hasConceptScore W2019968440C54355233 @default.
• W2019968440 hasConceptScore W2019968440C544153396 @default.
• W2019968440 hasConceptScore W2019968440C55493867 @default.
• W2019968440 hasConceptScore W2019968440C71240020 @default.

• next