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- W2019968716 abstract "Three consecutive pregnancies in which a cystic (n = 1) or solid (n = 2) fetal lung mass were diagnosed and followed using the combination of 3D (Kretz Voluson 730) ultrasound and fetal MRI. Measurements of the lung mass and contralateral lung volume were obtained. Fetal MRI (HASTE) was used to differentiate the aetiology of the mass. Post-mortem (case 2) or postoperative (case 1 and 3) specimen of the lung lesions were studied histologically in all cases. In the first case, a cystic lesion was seen in the upper part of the left lung of a fetus at 26 weeks of gestation. Sonographically, a bronchogenic cyst or a small CCAM type I was suspected. 3-D ultrasound was performed at 28 weeks' gestation showing normal volume of both lungs, and MRI showed a solid component to the mass in relation to the cyst, suggesting a mixed solid-cystic CCAM. This was confirmed on postnatal pathology. In two other cases, patient presented with a large homogenous hyperechogenic mass in one of the hemithorax at 20 and 27 weeks. Sonographically, differential diagnosis included unilateral bronchial stenosis, solid CCAM, congenital lobar emphysema and pulmonary sequestration. 3D ultrasound demonstrated a massively increased lung volume in the affected side and a reduced or normal in the contralateral side. MRI suggested CCAM in both cases. IUFD occurred in one of the two fetuses at 27 weeks with a pathology examination confirming a large CCAM, while the second baby was born alive at 38 weeks, and operated to get a solid mass removed, confirming a microcytic CCAM. In conclusion, CCAM can have a very variable antenatal presentation. These cases illustrate well the need for additional imaging techniques to evaluate these pregnancies. 3D ultrasound volumetric measurements of the lung masses and the contralateral lung were in correlation with the clinical or post-mortem findings. Fetal MRI provided can additional information leading on the exact aetiology of the lung mass." @default.
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- W2019968716 date "2004-08-01" @default.
- W2019968716 modified "2023-10-16" @default.
- W2019968716 title "P14.78: Role of 3D ultrasound and fetal MRI in the antenatal follow-up of fetuses with cystic adenomatoïd malformation of the lung (CCAM)" @default.
- W2019968716 doi "https://doi.org/10.1002/uog.1676" @default.
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