FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019968777> ?p ?o ?g. }

• W2019968777 endingPage "633" @default.
• W2019968777 startingPage "627" @default.
• W2019968777 abstract "Inconclusive test results often occur after prostate-specific antigen (PSA)–based screening for prostate cancer (PCa), leading to uncertainty on whether, how, and when to repeat testing. To develop and validate a prediction tool for the risk of PCa 4 yr after an initially negative screen. We analyzed data from 15 791 screen-negative men aged 55–70 yr at the initial screening round of the Rotterdam section of the European Randomized Study of Screening for Prostate Cancer. Follow-up and repeat screening at 4 yr showed either no PCa, low-risk PCa, or potentially high-risk PCa (defined as clinical stage >T2b and/or biopsy Gleason score ≥7 and/or PSA ≥10.0 ng/ml). A multinomial logistic regression analysis included initial screening data on age, PSA, digital rectal examination (DRE), family history, prostate volume, and having had a previous negative biopsy. The 4-yr risk predictions were validated with additional follow-up data up to 8 yr after initial screening. Positive family history and, especially, PSA level predicted PCa, whereas a previous negative biopsy or a large prostate volume reduced the likelihood of future PCa. The risk of having PCa 4 yr after an initially negative screen was 3.6% (interquartile range: 1.0–4.7%). Additional 8-yr follow-up data confirmed these predictions. Although data were based on sextant biopsies and a strict protocol-based biopsy indication, we suggest that men with a low predicted 4-yr risk (eg, ≤1.0%) could be rescreened at longer intervals or not at all, depending on competing risks, while men with an elevated 4-yr risk (eg, ≥5%) might benefit from immediate retesting. These findings need to be validated externally. This 4-yr future risk calculator, based on age, PSA, DRE, family history, prostate volume, and previous biopsy status, may be a promising tool for reducing uncertainty, unnecessary testing, and overdiagnosis of PCa." @default.
• W2019968777 created "2016-06-24" @default.
• W2019968777 creator A5001534857 @default.
• W2019968777 creator A5034477516 @default.
• W2019968777 creator A5035355889 @default.
• W2019968777 creator A5039867286 @default.
• W2019968777 creator A5041240078 @default.
• W2019968777 creator A5045276945 @default.
• W2019968777 creator A5083000708 @default.
• W2019968777 date "2013-04-01" @default.
• W2019968777 modified "2023-09-25" @default.
• W2019968777 title "A Calculator for Prostate Cancer Risk 4 Years After an Initially Negative Screen: Findings from ERSPC Rotterdam" @default.
• W2019968777 cites W1861816385 @default.
• W2019968777 cites W1954231945 @default.
• W2019968777 cites W197059223 @default.
• W2019968777 cites W1978177793 @default.
• W2019968777 cites W1980218659 @default.
• W2019968777 cites W2014176673 @default.
• W2019968777 cites W2026838241 @default.
• W2019968777 cites W2032956975 @default.
• W2019968777 cites W2039925428 @default.
• W2019968777 cites W2044039624 @default.
• W2019968777 cites W2050735593 @default.
• W2019968777 cites W2055159579 @default.
• W2019968777 cites W2057642029 @default.
• W2019968777 cites W2063908487 @default.
• W2019968777 cites W2074932800 @default.
• W2019968777 cites W2095445452 @default.
• W2019968777 cites W2106058419 @default.
• W2019968777 cites W2106519742 @default.
• W2019968777 cites W2118835332 @default.
• W2019968777 cites W2119819627 @default.
• W2019968777 cites W2119910794 @default.
• W2019968777 cites W2121103668 @default.
• W2019968777 cites W2125174047 @default.
• W2019968777 cites W2127261409 @default.
• W2019968777 cites W2127715602 @default.
• W2019968777 cites W2159803932 @default.
• W2019968777 cites W2160535888 @default.
• W2019968777 cites W2163098725 @default.
• W2019968777 cites W2163195821 @default.
• W2019968777 cites W2165416035 @default.
• W2019968777 doi "https://doi.org/10.1016/j.eururo.2012.07.029" @default.
• W2019968777 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22841675" @default.
• W2019968777 hasPublicationYear "2013" @default.
• W2019968777 type Work @default.
• W2019968777 sameAs 2019968777 @default.
• W2019968777 citedByCount "33" @default.
• W2019968777 countsByYear W20199687772013 @default.
• W2019968777 countsByYear W20199687772014 @default.
• W2019968777 countsByYear W20199687772015 @default.
• W2019968777 countsByYear W20199687772016 @default.
• W2019968777 countsByYear W20199687772017 @default.
• W2019968777 countsByYear W20199687772018 @default.
• W2019968777 countsByYear W20199687772019 @default.
• W2019968777 countsByYear W20199687772020 @default.
• W2019968777 countsByYear W20199687772021 @default.
• W2019968777 countsByYear W20199687772022 @default.
• W2019968777 crossrefType "journal-article" @default.
• W2019968777 hasAuthorship W2019968777A5001534857 @default.
• W2019968777 hasAuthorship W2019968777A5034477516 @default.
• W2019968777 hasAuthorship W2019968777A5035355889 @default.
• W2019968777 hasAuthorship W2019968777A5039867286 @default.
• W2019968777 hasAuthorship W2019968777A5041240078 @default.
• W2019968777 hasAuthorship W2019968777A5045276945 @default.
• W2019968777 hasAuthorship W2019968777A5083000708 @default.
• W2019968777 hasConcept C119060515 @default.
• W2019968777 hasConcept C121608353 @default.
• W2019968777 hasConcept C126322002 @default.
• W2019968777 hasConcept C126894567 @default.
• W2019968777 hasConcept C143998085 @default.
• W2019968777 hasConcept C2775934546 @default.
• W2019968777 hasConcept C2775941076 @default.
• W2019968777 hasConcept C2776235491 @default.
• W2019968777 hasConcept C2780101318 @default.
• W2019968777 hasConcept C2780192828 @default.
• W2019968777 hasConcept C2781179581 @default.
• W2019968777 hasConcept C2781217009 @default.
• W2019968777 hasConcept C2781406297 @default.
• W2019968777 hasConcept C29456083 @default.
• W2019968777 hasConcept C71924100 @default.
• W2019968777 hasConceptScore W2019968777C119060515 @default.
• W2019968777 hasConceptScore W2019968777C121608353 @default.
• W2019968777 hasConceptScore W2019968777C126322002 @default.
• W2019968777 hasConceptScore W2019968777C126894567 @default.
• W2019968777 hasConceptScore W2019968777C143998085 @default.
• W2019968777 hasConceptScore W2019968777C2775934546 @default.
• W2019968777 hasConceptScore W2019968777C2775941076 @default.
• W2019968777 hasConceptScore W2019968777C2776235491 @default.
• W2019968777 hasConceptScore W2019968777C2780101318 @default.
• W2019968777 hasConceptScore W2019968777C2780192828 @default.
• W2019968777 hasConceptScore W2019968777C2781179581 @default.
• W2019968777 hasConceptScore W2019968777C2781217009 @default.
• W2019968777 hasConceptScore W2019968777C2781406297 @default.
• W2019968777 hasConceptScore W2019968777C29456083 @default.
• W2019968777 hasConceptScore W2019968777C71924100 @default.
• W2019968777 hasIssue "4" @default.
• W2019968777 hasLocation W20199687771 @default.

• next