Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019973247> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2019973247 endingPage "37" @default.
- W2019973247 startingPage "33" @default.
- W2019973247 abstract "The objective of this study is to determine the effect of dyslipidemia on the plasma protein and lipoprotein distribution of haloperidol. In doing so, total plasma cholesterol and triglyceride levels were adjusted by adding differing volumes of concentrated low-density lipoproteins and very-low-density lipoproteins to normolipidemic plasma. Following the incubation of [3H]-haloperidol plus cold haloperidol (18 microg/ml) the plasma was separated into its lipoprotein and lipoprotein deficient fractions by density gradient ultra centrifugation and [3H]-haloperidol distribution was determined. Our results revealed a significant positive correlation between total cholesterol concentration and haloperidol recovery in the low-density lipoprotein fraction (r=0.975, df=13, P<0.005). A positive correlation was also observed between total plasma triglyceride concentration and haloperidol recovery from both the very low-density lipoprotein (r=0.965, df=16, P<0.002) and low-density lipoprotein fractions (r=0.935, df=16, P<0.005). This redistribution was the result of haloperidol leaving the lipoprotein-deficient fraction were it is primarily bound to albumin and alpha(1)-acid glycoprotein. This redistribution of haloperidol may influence its clinical efficacy." @default.
- W2019973247 created "2016-06-24" @default.
- W2019973247 creator A5006507316 @default.
- W2019973247 creator A5052823521 @default.
- W2019973247 creator A5076806422 @default.
- W2019973247 date "2003-01-01" @default.
- W2019973247 modified "2023-09-27" @default.
- W2019973247 title "The influence of dyslipidemia on the plasma protein and lipoprotein distribution of haloperidol" @default.
- W2019973247 cites W1985138005 @default.
- W2019973247 cites W1989974319 @default.
- W2019973247 cites W1995880596 @default.
- W2019973247 cites W2010794707 @default.
- W2019973247 cites W2017082161 @default.
- W2019973247 cites W2020966839 @default.
- W2019973247 cites W202567121 @default.
- W2019973247 cites W2031600335 @default.
- W2019973247 cites W2039285681 @default.
- W2019973247 cites W2039788401 @default.
- W2019973247 cites W2045671960 @default.
- W2019973247 cites W2060676930 @default.
- W2019973247 cites W2068599970 @default.
- W2019973247 cites W2075539073 @default.
- W2019973247 cites W208166447 @default.
- W2019973247 cites W2089671853 @default.
- W2019973247 cites W2120376279 @default.
- W2019973247 cites W2162222189 @default.
- W2019973247 cites W2407410715 @default.
- W2019973247 cites W2409620807 @default.
- W2019973247 cites W2415891338 @default.
- W2019973247 cites W4248391713 @default.
- W2019973247 cites W70282862 @default.
- W2019973247 doi "https://doi.org/10.1016/s0924-977x(02)00078-0" @default.
- W2019973247 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12480120" @default.
- W2019973247 hasPublicationYear "2003" @default.
- W2019973247 type Work @default.
- W2019973247 sameAs 2019973247 @default.
- W2019973247 citedByCount "8" @default.
- W2019973247 countsByYear W20199732472012 @default.
- W2019973247 countsByYear W20199732472014 @default.
- W2019973247 countsByYear W20199732472017 @default.
- W2019973247 countsByYear W20199732472019 @default.
- W2019973247 crossrefType "journal-article" @default.
- W2019973247 hasAuthorship W2019973247A5006507316 @default.
- W2019973247 hasAuthorship W2019973247A5052823521 @default.
- W2019973247 hasAuthorship W2019973247A5076806422 @default.
- W2019973247 hasConcept C126322002 @default.
- W2019973247 hasConcept C134018914 @default.
- W2019973247 hasConcept C185592680 @default.
- W2019973247 hasConcept C2776104379 @default.
- W2019973247 hasConcept C2778096610 @default.
- W2019973247 hasConcept C2778163477 @default.
- W2019973247 hasConcept C2778913445 @default.
- W2019973247 hasConcept C2779620165 @default.
- W2019973247 hasConcept C2780072125 @default.
- W2019973247 hasConcept C2780948584 @default.
- W2019973247 hasConcept C513476851 @default.
- W2019973247 hasConcept C55493867 @default.
- W2019973247 hasConcept C555293320 @default.
- W2019973247 hasConcept C71924100 @default.
- W2019973247 hasConcept C8243546 @default.
- W2019973247 hasConceptScore W2019973247C126322002 @default.
- W2019973247 hasConceptScore W2019973247C134018914 @default.
- W2019973247 hasConceptScore W2019973247C185592680 @default.
- W2019973247 hasConceptScore W2019973247C2776104379 @default.
- W2019973247 hasConceptScore W2019973247C2778096610 @default.
- W2019973247 hasConceptScore W2019973247C2778163477 @default.
- W2019973247 hasConceptScore W2019973247C2778913445 @default.
- W2019973247 hasConceptScore W2019973247C2779620165 @default.
- W2019973247 hasConceptScore W2019973247C2780072125 @default.
- W2019973247 hasConceptScore W2019973247C2780948584 @default.
- W2019973247 hasConceptScore W2019973247C513476851 @default.
- W2019973247 hasConceptScore W2019973247C55493867 @default.
- W2019973247 hasConceptScore W2019973247C555293320 @default.
- W2019973247 hasConceptScore W2019973247C71924100 @default.
- W2019973247 hasConceptScore W2019973247C8243546 @default.
- W2019973247 hasIssue "1" @default.
- W2019973247 hasLocation W20199732471 @default.
- W2019973247 hasLocation W20199732472 @default.
- W2019973247 hasOpenAccess W2019973247 @default.
- W2019973247 hasPrimaryLocation W20199732471 @default.
- W2019973247 hasRelatedWork W1976602105 @default.
- W2019973247 hasRelatedWork W1996561303 @default.
- W2019973247 hasRelatedWork W2040092002 @default.
- W2019973247 hasRelatedWork W2103393903 @default.
- W2019973247 hasRelatedWork W2134715975 @default.
- W2019973247 hasRelatedWork W2154562089 @default.
- W2019973247 hasRelatedWork W2306670624 @default.
- W2019973247 hasRelatedWork W2413861530 @default.
- W2019973247 hasRelatedWork W3155576213 @default.
- W2019973247 hasRelatedWork W4254741097 @default.
- W2019973247 hasVolume "13" @default.
- W2019973247 isParatext "false" @default.
- W2019973247 isRetracted "false" @default.
- W2019973247 magId "2019973247" @default.
- W2019973247 workType "article" @default.