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• W2019974706 abstract "The relationship between extracellular pH and intracellular calcium concentration ([Ca2+] 1) in primary culture of neonatal rat astrocytes with Ca2+-indicator dye indo-1/acetoxymethyl ester and a confocal microscope was investigated. In 65 of 86 astrocytes studied, lowering extracellular pH by changing the perfusate solution from pH 7.4 to 6.4 was followed by increases in [Ca2+] 1 in cytoplasm. The increases in [Ca2+] 1 were seen on stimulation and/or during reperfusion. Of all the cells, 45.4% showed a transient pattern and 30.2% manifested a sustained pattern. The results suggest that a short interval but excessive acidic stimulation may be one of the signals that raises [Ca2+] 1 in a certain population of cerebral astrocytes." @default.
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• W2019974706 date "1997-01-01" @default.
• W2019974706 modified "2023-09-26" @default.
• W2019974706 title "Lowering Extracellular pH Raises Intracellular Calcium in Cultured Rat Astrocytes." @default.
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• W2019974706 doi "https://doi.org/10.1267/ahc.30.221" @default.
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