FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019977336> ?p ?o ?g. }

• W2019977336 endingPage "52" @default.
• W2019977336 startingPage "47" @default.
• W2019977336 abstract "Conflicting recommendations regarding antibiotic prophylaxis for contacts of patients with invasive group A streptococcal (GAS) infection exist. Close contacts of patients with such severe and rapidly progressive disease often strongly appeal to the treating clinicians for antimicrobial treatment to prevent additional cases. We aimed to use an approach based on pharyngeal culture testing of contacts and targeted antibiotic prophylaxis.A large throat swab survey including 105 contacts was undertaken after a fulminant and fatal case of GAS necrotizing fasciitis. GAS strains were characterized by emm typing and antimicrobial susceptibility to 7 antibiotics. The presence of 30 virulence determinants was determined by polymerase chain reaction and sequencing.The GAS isolate recovered from the index patient was an M1T1 GAS clone susceptible to all antimicrobial agents tested. The same clone was present in the throat of 36% of close contacts who had exposure to the index patient (family households and classroom contacts) for >24 hours/week, whereas the strain was present in only 2% of the other contacts.Although the study does not allow firm conclusions to be drawn as to whether antibiotic prophylaxis is effective, we describe a practical approach, including an educational campaign and targeted antibiotic treatment to close contacts who have been exposed to an index patient for > 24 hours/week before the initial disease onset." @default.
• W2019977336 created "2016-06-24" @default.
• W2019977336 creator A5010049125 @default.
• W2019977336 creator A5015035527 @default.
• W2019977336 creator A5020999460 @default.
• W2019977336 creator A5040302770 @default.
• W2019977336 creator A5056433714 @default.
• W2019977336 creator A5062954764 @default.
• W2019977336 creator A5069014035 @default.
• W2019977336 date "2014-10-30" @default.
• W2019977336 modified "2023-09-27" @default.
• W2019977336 title "Management of Contacts of Patients With Severe Invasive Group A Streptococcal Infection" @default.
• W2019977336 cites W1843935540 @default.
• W2019977336 cites W1966875214 @default.
• W2019977336 cites W1971967698 @default.
• W2019977336 cites W1978532273 @default.
• W2019977336 cites W1980858568 @default.
• W2019977336 cites W1984023028 @default.
• W2019977336 cites W1990356874 @default.
• W2019977336 cites W1993406826 @default.
• W2019977336 cites W2000765045 @default.
• W2019977336 cites W2009969100 @default.
• W2019977336 cites W2010719216 @default.
• W2019977336 cites W2013074835 @default.
• W2019977336 cites W2035194773 @default.
• W2019977336 cites W2036345863 @default.
• W2019977336 cites W2040930422 @default.
• W2019977336 cites W2041760492 @default.
• W2019977336 cites W2067808303 @default.
• W2019977336 cites W2082068993 @default.
• W2019977336 cites W2088159995 @default.
• W2019977336 cites W2097882837 @default.
• W2019977336 cites W2100549943 @default.
• W2019977336 cites W2102267665 @default.
• W2019977336 cites W2109937748 @default.
• W2019977336 cites W2114318936 @default.
• W2019977336 cites W2115827828 @default.
• W2019977336 cites W2116235763 @default.
• W2019977336 cites W2120015071 @default.
• W2019977336 cites W2124651059 @default.
• W2019977336 cites W2125623581 @default.
• W2019977336 cites W2132715940 @default.
• W2019977336 cites W2133886029 @default.
• W2019977336 cites W2137786976 @default.
• W2019977336 cites W2140031610 @default.
• W2019977336 cites W2146381766 @default.
• W2019977336 cites W2154819732 @default.
• W2019977336 cites W2158795319 @default.
• W2019977336 cites W2166626843 @default.
• W2019977336 cites W2221714924 @default.
• W2019977336 cites W2315029565 @default.
• W2019977336 cites W2418654519 @default.
• W2019977336 cites W3154259764 @default.
• W2019977336 cites W4301053517 @default.
• W2019977336 cites W4323873759 @default.
• W2019977336 doi "https://doi.org/10.1093/jpids/piu107" @default.
• W2019977336 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26908491" @default.
• W2019977336 hasPublicationYear "2014" @default.
• W2019977336 type Work @default.
• W2019977336 sameAs 2019977336 @default.
• W2019977336 citedByCount "12" @default.
• W2019977336 countsByYear W20199773362017 @default.
• W2019977336 countsByYear W20199773362018 @default.
• W2019977336 countsByYear W20199773362019 @default.
• W2019977336 countsByYear W20199773362020 @default.
• W2019977336 countsByYear W20199773362021 @default.
• W2019977336 countsByYear W20199773362022 @default.
• W2019977336 countsByYear W20199773362023 @default.
• W2019977336 crossrefType "journal-article" @default.
• W2019977336 hasAuthorship W2019977336A5010049125 @default.
• W2019977336 hasAuthorship W2019977336A5015035527 @default.
• W2019977336 hasAuthorship W2019977336A5020999460 @default.
• W2019977336 hasAuthorship W2019977336A5040302770 @default.
• W2019977336 hasAuthorship W2019977336A5056433714 @default.
• W2019977336 hasAuthorship W2019977336A5062954764 @default.
• W2019977336 hasAuthorship W2019977336A5069014035 @default.
• W2019977336 hasBestOaLocation W20199773361 @default.
• W2019977336 hasConcept C126322002 @default.
• W2019977336 hasConcept C141071460 @default.
• W2019977336 hasConcept C177713679 @default.
• W2019977336 hasConcept C187212893 @default.
• W2019977336 hasConcept C2776989088 @default.
• W2019977336 hasConcept C2777217379 @default.
• W2019977336 hasConcept C2778276568 @default.
• W2019977336 hasConcept C2778602436 @default.
• W2019977336 hasConcept C2779134260 @default.
• W2019977336 hasConcept C2779279270 @default.
• W2019977336 hasConcept C2781107259 @default.
• W2019977336 hasConcept C2781381541 @default.
• W2019977336 hasConcept C447327 @default.
• W2019977336 hasConcept C4937899 @default.
• W2019977336 hasConcept C501593827 @default.
• W2019977336 hasConcept C523546767 @default.
• W2019977336 hasConcept C54355233 @default.
• W2019977336 hasConcept C71924100 @default.
• W2019977336 hasConcept C86803240 @default.
• W2019977336 hasConcept C89423630 @default.
• W2019977336 hasConceptScore W2019977336C126322002 @default.

• next