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- W2019977567 abstract "The signal transduction pathway involved in radiation-induced apoptosis remains unclear, especially as regards the site at which the primary effect of radiation occurs. In this study, we demonstrate that cytochrome c may be released from mitochondria into the cytosol after irradiation, but that direct irradiation of isolated mitochondria induces no elevation of cytochrome c release. These observations suggest that cytochrome c and mitochondria may be involved in the radiation-induced apoptotic pathway, but mitochondria might not be a target of radiation, and that a signal transduction pathway from an unknown target might exist upstream of mitochondria during radiation-induced apoptosis." @default.
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- W2019977567 date "1998-10-01" @default.
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- W2019977567 title "Elevation of Cytoplasmic Cytochromecin Radiation-induced Apoptosis" @default.
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- W2019977567 doi "https://doi.org/10.1111/j.1349-7006.1998.tb00500.x" @default.
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