Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019977660> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2019977660 endingPage "1197" @default.
- W2019977660 startingPage "1195" @default.
- W2019977660 abstract "The inhibitory effect of the putative adenosine A2 receptor agonist 5'-N-ethylcarboxamidoadenosine (NECA) on acetylcholine release from the stimulated guinea pig ileum preparation and the nature of its antagonism by theophylline were investigated. NECA was shown to inhibit the response of the ileum preparation in a dose-dependent fashion, and an EC50 value of 1.62 X 10(-8) M was determined. This value was comparable with that determined for the A1 receptor agonist N6-R-phenylisopropyladenosine (R-PIA) (2.57 X 10(-8) M) using the same preparation. Competitive antagonism of the inhibitory effect of NECA by theophylline was quantitated and a pA2 value of 5.04 for the methylxanthine was obtained. This value was similar to those obtained previously for R-PIA and adenosine itself and suggests that these nucleosides may be interacting with the same receptor site on myenteric nerve endings. These findings do not permit the designation of the receptor as an A1 or A2 subtype according to current criteria." @default.
- W2019977660 created "2016-06-24" @default.
- W2019977660 creator A5038344990 @default.
- W2019977660 creator A5048388770 @default.
- W2019977660 date "1985-09-01" @default.
- W2019977660 modified "2023-09-24" @default.
- W2019977660 title "Antagonism by theophylline of the adenosine receptor agonist 5′-N-ethykarboxamidoadenosine at the guinea pig ileum" @default.
- W2019977660 doi "https://doi.org/10.1139/y85-196" @default.
- W2019977660 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2996734" @default.
- W2019977660 hasPublicationYear "1985" @default.
- W2019977660 type Work @default.
- W2019977660 sameAs 2019977660 @default.
- W2019977660 citedByCount "4" @default.
- W2019977660 crossrefType "journal-article" @default.
- W2019977660 hasAuthorship W2019977660A5038344990 @default.
- W2019977660 hasAuthorship W2019977660A5048388770 @default.
- W2019977660 hasConcept C126322002 @default.
- W2019977660 hasConcept C134018914 @default.
- W2019977660 hasConcept C170493617 @default.
- W2019977660 hasConcept C185592680 @default.
- W2019977660 hasConcept C2776991684 @default.
- W2019977660 hasConcept C2777226302 @default.
- W2019977660 hasConcept C2777383412 @default.
- W2019977660 hasConcept C2778095195 @default.
- W2019977660 hasConcept C2778815084 @default.
- W2019977660 hasConcept C2778938600 @default.
- W2019977660 hasConcept C67907053 @default.
- W2019977660 hasConcept C71924100 @default.
- W2019977660 hasConcept C86803240 @default.
- W2019977660 hasConcept C98274493 @default.
- W2019977660 hasConceptScore W2019977660C126322002 @default.
- W2019977660 hasConceptScore W2019977660C134018914 @default.
- W2019977660 hasConceptScore W2019977660C170493617 @default.
- W2019977660 hasConceptScore W2019977660C185592680 @default.
- W2019977660 hasConceptScore W2019977660C2776991684 @default.
- W2019977660 hasConceptScore W2019977660C2777226302 @default.
- W2019977660 hasConceptScore W2019977660C2777383412 @default.
- W2019977660 hasConceptScore W2019977660C2778095195 @default.
- W2019977660 hasConceptScore W2019977660C2778815084 @default.
- W2019977660 hasConceptScore W2019977660C2778938600 @default.
- W2019977660 hasConceptScore W2019977660C67907053 @default.
- W2019977660 hasConceptScore W2019977660C71924100 @default.
- W2019977660 hasConceptScore W2019977660C86803240 @default.
- W2019977660 hasConceptScore W2019977660C98274493 @default.
- W2019977660 hasIssue "9" @default.
- W2019977660 hasLocation W20199776601 @default.
- W2019977660 hasLocation W20199776602 @default.
- W2019977660 hasOpenAccess W2019977660 @default.
- W2019977660 hasPrimaryLocation W20199776601 @default.
- W2019977660 hasRelatedWork W2000623971 @default.
- W2019977660 hasRelatedWork W2003866428 @default.
- W2019977660 hasRelatedWork W2004260211 @default.
- W2019977660 hasRelatedWork W2017770252 @default.
- W2019977660 hasRelatedWork W2019977660 @default.
- W2019977660 hasRelatedWork W2026105695 @default.
- W2019977660 hasRelatedWork W2043548718 @default.
- W2019977660 hasRelatedWork W2071480419 @default.
- W2019977660 hasRelatedWork W2086098588 @default.
- W2019977660 hasRelatedWork W2101277166 @default.
- W2019977660 hasVolume "63" @default.
- W2019977660 isParatext "false" @default.
- W2019977660 isRetracted "false" @default.
- W2019977660 magId "2019977660" @default.
- W2019977660 workType "article" @default.