FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019978536> ?p ?o ?g. }

• W2019978536 endingPage "3407" @default.
• W2019978536 startingPage "3405" @default.
• W2019978536 abstract "Induction therapy improves graft outcomes in kidney transplant recipients (KTRs). We aimed to compare the incidences of antibody-mediated rejection (AMR) and acute cellular rejection (ACR) as well as graft and patient outcomes in KTRs who underwent induction with alemtuzumab versus rabbit-antithymocyte globulin (r-ATG).This was a single-center retrospective study involving patients who underwent kidney transplantation between January 2009 and December 2011 after receiving induction therapy with either alemtuzumab or r-ATG. Maintenance immunosuppression included tacrolimus and mycophenolate mofetil with early steroid withdrawal. Acute rejection was diagnosed using allograft biopsy.Among the 108 study patients, 68 received alemtuzumab and 40 got r-ATG. There was a significantly higher incidence of AMR (15% vs 2.5%; P = .008) and similar incidence of ACR (4.4% vs 10%; P = .69) for alemtuzumab versus r-ATG groups. One-year serum creatinine levels (l.68 ± 0.8 mg/dL vs 1.79 ± 1.8 mg/dL; P = .66) as well as graft (91.1 ± 3.5% vs 94.5 ± 3.8%; P = .48) and patient (93.8 ± 3.0% vs 96.4 ± 3.5%; P = .92) survivals were similar for the alemtuzumab versus the r-ATG groups.Our study showed a higher incidence of AMR and similar incidence of ACR in KTRs who underwent induction with alemtuzumab compared with those who received r-ATG and were maintained on tacrolimus and MMF. This was despite a lower HLA mismatch in the alemtuzumab group. One-year graft survival, patient survival, and allograft function were similar. Inadequate B-cell suppression by alemtuzumab as well as altered phenotypic and functional properties of repopulating B cells could be contributing to heightened risk of AMR in these patients." @default.
• W2019978536 created "2016-06-24" @default.
• W2019978536 creator A5011251914 @default.
• W2019978536 creator A5023787476 @default.
• W2019978536 creator A5025316533 @default.
• W2019978536 creator A5040807383 @default.
• W2019978536 creator A5056903657 @default.
• W2019978536 creator A5060348914 @default.
• W2019978536 creator A5065781755 @default.
• W2019978536 date "2014-12-01" @default.
• W2019978536 modified "2023-09-30" @default.
• W2019978536 title "Alemtuzumab Induction and Antibody-Mediated Rejection in Kidney Transplantation" @default.
• W2019978536 cites W1588284792 @default.
• W2019978536 cites W1753626413 @default.
• W2019978536 cites W1949819251 @default.
• W2019978536 cites W1984811897 @default.
• W2019978536 cites W2006210549 @default.
• W2019978536 cites W2019333652 @default.
• W2019978536 cites W2081695157 @default.
• W2019978536 cites W2098773501 @default.
• W2019978536 cites W2109528079 @default.
• W2019978536 cites W2127536951 @default.
• W2019978536 cites W2141854245 @default.
• W2019978536 cites W2329264557 @default.
• W2019978536 doi "https://doi.org/10.1016/j.transproceed.2014.08.037" @default.
• W2019978536 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25498060" @default.
• W2019978536 hasPublicationYear "2014" @default.
• W2019978536 type Work @default.
• W2019978536 sameAs 2019978536 @default.
• W2019978536 citedByCount "15" @default.
• W2019978536 countsByYear W20199785362015 @default.
• W2019978536 countsByYear W20199785362016 @default.
• W2019978536 countsByYear W20199785362017 @default.
• W2019978536 countsByYear W20199785362018 @default.
• W2019978536 countsByYear W20199785362019 @default.
• W2019978536 countsByYear W20199785362020 @default.
• W2019978536 countsByYear W20199785362021 @default.
• W2019978536 countsByYear W20199785362022 @default.
• W2019978536 countsByYear W20199785362023 @default.
• W2019978536 crossrefType "journal-article" @default.
• W2019978536 hasAuthorship W2019978536A5011251914 @default.
• W2019978536 hasAuthorship W2019978536A5023787476 @default.
• W2019978536 hasAuthorship W2019978536A5025316533 @default.
• W2019978536 hasAuthorship W2019978536A5040807383 @default.
• W2019978536 hasAuthorship W2019978536A5056903657 @default.
• W2019978536 hasAuthorship W2019978536A5060348914 @default.
• W2019978536 hasAuthorship W2019978536A5065781755 @default.
• W2019978536 hasConcept C120665830 @default.
• W2019978536 hasConcept C121332964 @default.
• W2019978536 hasConcept C126322002 @default.
• W2019978536 hasConcept C126894567 @default.
• W2019978536 hasConcept C141071460 @default.
• W2019978536 hasConcept C159641895 @default.
• W2019978536 hasConcept C2776694085 @default.
• W2019978536 hasConcept C2777630719 @default.
• W2019978536 hasConcept C2779015954 @default.
• W2019978536 hasConcept C2780252810 @default.
• W2019978536 hasConcept C2780303639 @default.
• W2019978536 hasConcept C2780306776 @default.
• W2019978536 hasConcept C2909675724 @default.
• W2019978536 hasConcept C2911091166 @default.
• W2019978536 hasConcept C2991767035 @default.
• W2019978536 hasConcept C61511704 @default.
• W2019978536 hasConcept C71924100 @default.
• W2019978536 hasConcept C90924648 @default.
• W2019978536 hasConceptScore W2019978536C120665830 @default.
• W2019978536 hasConceptScore W2019978536C121332964 @default.
• W2019978536 hasConceptScore W2019978536C126322002 @default.
• W2019978536 hasConceptScore W2019978536C126894567 @default.
• W2019978536 hasConceptScore W2019978536C141071460 @default.
• W2019978536 hasConceptScore W2019978536C159641895 @default.
• W2019978536 hasConceptScore W2019978536C2776694085 @default.
• W2019978536 hasConceptScore W2019978536C2777630719 @default.
• W2019978536 hasConceptScore W2019978536C2779015954 @default.
• W2019978536 hasConceptScore W2019978536C2780252810 @default.
• W2019978536 hasConceptScore W2019978536C2780303639 @default.
• W2019978536 hasConceptScore W2019978536C2780306776 @default.
• W2019978536 hasConceptScore W2019978536C2909675724 @default.
• W2019978536 hasConceptScore W2019978536C2911091166 @default.
• W2019978536 hasConceptScore W2019978536C2991767035 @default.
• W2019978536 hasConceptScore W2019978536C61511704 @default.
• W2019978536 hasConceptScore W2019978536C71924100 @default.
• W2019978536 hasConceptScore W2019978536C90924648 @default.
• W2019978536 hasIssue "10" @default.
• W2019978536 hasLocation W20199785361 @default.
• W2019978536 hasLocation W20199785362 @default.
• W2019978536 hasOpenAccess W2019978536 @default.
• W2019978536 hasPrimaryLocation W20199785361 @default.
• W2019978536 hasRelatedWork W1486584413 @default.
• W2019978536 hasRelatedWork W1511302864 @default.
• W2019978536 hasRelatedWork W1600771015 @default.
• W2019978536 hasRelatedWork W2037825761 @default.
• W2019978536 hasRelatedWork W2052365623 @default.
• W2019978536 hasRelatedWork W2064425530 @default.
• W2019978536 hasRelatedWork W2065112245 @default.
• W2019978536 hasRelatedWork W2065729608 @default.
• W2019978536 hasRelatedWork W2077996663 @default.
• W2019978536 hasRelatedWork W2087086071 @default.

• next