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- W2019980691 abstract "Lysinuric protein intolerance (LPI) is a rare recessively inherited disease in which one of the fundamental physiological defects is in the mechanism by which diamino acids are transported by the kidney. The purpose of the present studies was to examine that mechanism in four controls and seven patients with LPI. Two types of studies were conducted. In the first set, the renal handling of l-arginine and l-ornithine was evaluated by gradually increasing the plasma concentration of each of these amino acids by constant infusion techniques. In the second set of studies, the possible existence of competitive inhibition between l-arginine, l-ornithine, and l-lysine was examined." @default.
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- W2019980691 title "Renal Handling of Diamino Acids in Lysinuric Protein Intolerance" @default.
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- W2019980691 doi "https://doi.org/10.1172/jci107753" @default.
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