FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019981566> ?p ?o ?g. }

• W2019981566 endingPage "633" @default.
• W2019981566 startingPage "624" @default.
• W2019981566 abstract "Adenoviral based gene therapy has been used in clinical trials in control of advanced prostate cancer. In this study, a promising conditionally replicating adenovirus (CRAd) driven by a tissue specific bone sialoprotein promoter in controlling prostate cancer both in vitro and in vivo is demonstrated. C4-2B, an androgen-independent prostate cancer cell line, was treated with PBS, Ad-BSP-TK, or the Ad-BSP-E1a in vitro, and in subcutaneous and intraosseous xenographs. Cell proliferation, PSA level in condition medium, tumor volume, and/or serum PSA were followed. The growth of C4-2B and the PSA production was dramatically suppressed by Ad-BSP-E1a at very low dosage (0.3 MOI) compared with PBS and Ad-BSP-TK treatment in vitro. In the subcutaneous model, the tumor volume was significantly lower statistically in the Ad-BSP-E1a treated group than the Ad-BSP-TK control group (P = 0.02). In the intraosseous model, the mice treated in the Ad-BSP-E1a treatment group demonstrated a significant lower PSA compared to that in the control group (P < 0.01) at week 8 and week 16 post-treatment. The CRAd Ad-BSP-E1a revealed potential in treating prostate cancer in this model system. Using viral or none-viral mediated gene therapy to treat prostate carcinoma continues to be a potential avenue to treat afflicted men with prostate cancer." @default.
• W2019981566 created "2016-06-24" @default.
• W2019981566 creator A5009958261 @default.
• W2019981566 creator A5038077662 @default.
• W2019981566 creator A5044760645 @default.
• W2019981566 creator A5060931986 @default.
• W2019981566 creator A5068858295 @default.
• W2019981566 date "2011-11-01" @default.
• W2019981566 modified "2023-10-02" @default.
• W2019981566 title "Conditionally replicating adenovirus therapy utilizing bone sialoprotein promoter (Ad-BSP-E1a) in an in vivo study of treating androgen-independent intraosseous prostate cancer" @default.
• W2019981566 cites W1969745650 @default.
• W2019981566 cites W1972601062 @default.
• W2019981566 cites W1975577875 @default.
• W2019981566 cites W1978588183 @default.
• W2019981566 cites W1981937959 @default.
• W2019981566 cites W1990073456 @default.
• W2019981566 cites W1997389064 @default.
• W2019981566 cites W2000208656 @default.
• W2019981566 cites W2001471842 @default.
• W2019981566 cites W2013023284 @default.
• W2019981566 cites W2013619396 @default.
• W2019981566 cites W2015597117 @default.
• W2019981566 cites W2019583067 @default.
• W2019981566 cites W2023166781 @default.
• W2019981566 cites W2028600721 @default.
• W2019981566 cites W2033890749 @default.
• W2019981566 cites W2041649745 @default.
• W2019981566 cites W2041684900 @default.
• W2019981566 cites W2045575161 @default.
• W2019981566 cites W2054127675 @default.
• W2019981566 cites W2058680827 @default.
• W2019981566 cites W2059085904 @default.
• W2019981566 cites W2084049907 @default.
• W2019981566 cites W2085834739 @default.
• W2019981566 cites W2086026048 @default.
• W2019981566 cites W2109218792 @default.
• W2019981566 cites W2113503664 @default.
• W2019981566 cites W2115489663 @default.
• W2019981566 cites W2121435941 @default.
• W2019981566 cites W2124843577 @default.
• W2019981566 cites W2126482839 @default.
• W2019981566 cites W2128089900 @default.
• W2019981566 cites W2130691538 @default.
• W2019981566 cites W2145262726 @default.
• W2019981566 cites W2161278579 @default.
• W2019981566 cites W2325520886 @default.
• W2019981566 cites W4231334043 @default.
• W2019981566 cites W84075068 @default.
• W2019981566 doi "https://doi.org/10.1016/j.urolonc.2009.08.012" @default.
• W2019981566 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19963408" @default.
• W2019981566 hasPublicationYear "2011" @default.
• W2019981566 type Work @default.
• W2019981566 sameAs 2019981566 @default.
• W2019981566 citedByCount "4" @default.
• W2019981566 countsByYear W20199815662012 @default.
• W2019981566 countsByYear W20199815662013 @default.
• W2019981566 countsByYear W20199815662017 @default.
• W2019981566 countsByYear W20199815662018 @default.
• W2019981566 crossrefType "journal-article" @default.
• W2019981566 hasAuthorship W2019981566A5009958261 @default.
• W2019981566 hasAuthorship W2019981566A5038077662 @default.
• W2019981566 hasAuthorship W2019981566A5044760645 @default.
• W2019981566 hasAuthorship W2019981566A5060931986 @default.
• W2019981566 hasAuthorship W2019981566A5068858295 @default.
• W2019981566 hasConcept C104317684 @default.
• W2019981566 hasConcept C111599444 @default.
• W2019981566 hasConcept C121608353 @default.
• W2019981566 hasConcept C126322002 @default.
• W2019981566 hasConcept C131075544 @default.
• W2019981566 hasConcept C143998085 @default.
• W2019981566 hasConcept C150903083 @default.
• W2019981566 hasConcept C160160445 @default.
• W2019981566 hasConcept C181199279 @default.
• W2019981566 hasConcept C207001950 @default.
• W2019981566 hasConcept C2776235491 @default.
• W2019981566 hasConcept C2776432469 @default.
• W2019981566 hasConcept C2780192828 @default.
• W2019981566 hasConcept C502942594 @default.
• W2019981566 hasConcept C55493867 @default.
• W2019981566 hasConcept C71924100 @default.
• W2019981566 hasConcept C86803240 @default.
• W2019981566 hasConceptScore W2019981566C104317684 @default.
• W2019981566 hasConceptScore W2019981566C111599444 @default.
• W2019981566 hasConceptScore W2019981566C121608353 @default.
• W2019981566 hasConceptScore W2019981566C126322002 @default.
• W2019981566 hasConceptScore W2019981566C131075544 @default.
• W2019981566 hasConceptScore W2019981566C143998085 @default.
• W2019981566 hasConceptScore W2019981566C150903083 @default.
• W2019981566 hasConceptScore W2019981566C160160445 @default.
• W2019981566 hasConceptScore W2019981566C181199279 @default.
• W2019981566 hasConceptScore W2019981566C207001950 @default.
• W2019981566 hasConceptScore W2019981566C2776235491 @default.
• W2019981566 hasConceptScore W2019981566C2776432469 @default.
• W2019981566 hasConceptScore W2019981566C2780192828 @default.
• W2019981566 hasConceptScore W2019981566C502942594 @default.
• W2019981566 hasConceptScore W2019981566C55493867 @default.
• W2019981566 hasConceptScore W2019981566C71924100 @default.
• W2019981566 hasConceptScore W2019981566C86803240 @default.

• next