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• W2019986995 abstract "Approximately equieffective doses of d- and l-amphetamine, using suppression of operant fixed-ratio responding for food reinforcement as the determinant of potency, were compared for their ability to alter the disposition of the major and minor metabolites of NE in push-pull perfusates from rat brain lateral ventricle. While 3 mg d-amphetamine/kg and 6 mg l-amphetamine/kg both increased total 3H and the relative amounts of the minor metabolites 3H-normetanephrine and 3-dihydroxymandelic acid, only l-amphetamine caused a significant increase in the major 3H-NE metabolite, methoxyhydroxyphenylethylene-glycol. The data is discussed in relation to the abilities of the isomers of amphetamine to stereoselectively interact with noradrenergic neurons at doses that produce similar effects upon operant behavior." @default.
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• W2019986995 date "1976-05-01" @default.
• W2019986995 modified "2023-09-26" @default.
• W2019986995 title "Differential actions of d- and l-amphetamine on the metabolism of 3H-norepinephrine in rat brain" @default.
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• W2019986995 doi "https://doi.org/10.1016/0091-3057(76)90196-9" @default.
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