FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019998722> ?p ?o ?g. }

• W2019998722 endingPage "1764" @default.
• W2019998722 startingPage "1753" @default.
• W2019998722 abstract "Haemoglobins bearing reactive sulfhydryl groups have been shown to be able to interplay with glutathione in some detoxification processes. Blood from different mouse strains commonly used as experimental animal models, i.e., C57, DBA and ICR, was treated with oxidants with the aim of evaluating: (i) the involvement of protein SH groups in oxido-reductive reactions that are commonly carried out by glutathione and (ii) the impact of this phenomenon on blood-mediated metabolism of thiol reactants. All the main forms of glutathione (reduced, disulfide, and mixed disulfide with haemoglobin) were measured after oxidant treatment. Significant differences were found among the studied strains: DBA mice formed preferably mixed disulfides instead of glutathione disulfide, whereas the opposite behaviour was shown by C57 mice. Unexpectedly, the ICR strain resulted to be composed of three different subgroups (ICRa, ICRb, and ICRc), with the ICRa behaving similarly to the DBA strain, ICRc to the C57 strain, and ICRc showing an intermediate behaviour. These results are due to the different number of haemoglobin SH groups in the studied mouse strains. In particular, additional fast-reacting SH groups were found in haemoglobin from DBA, ICRa, and ICRb mice, but not in the C57 and ICRc strain. These differences were also reflected in the susceptibility of haemoglobin to dimerize and in its ability to react with S-nitrosocysteine. Because of the widely different reactivity of haemoglobin cysteinyl residues, the mouse strains examined are an interesting but complicated model in which to study the pharmacological and toxicological action of some drugs." @default.
• W2019998722 created "2016-06-24" @default.
• W2019998722 creator A5018604525 @default.
• W2019998722 creator A5021943550 @default.
• W2019998722 creator A5060369739 @default.
• W2019998722 creator A5069021426 @default.
• W2019998722 creator A5073697768 @default.
• W2019998722 creator A5078717520 @default.
• W2019998722 creator A5088313319 @default.
• W2019998722 date "2006-06-01" @default.
• W2019998722 modified "2023-10-16" @default.
• W2019998722 title "Metabolism of oxidants by blood from different mouse strains" @default.
• W2019998722 cites W1569873526 @default.
• W2019998722 cites W1573313908 @default.
• W2019998722 cites W1598978469 @default.
• W2019998722 cites W1964902531 @default.
• W2019998722 cites W1971306064 @default.
• W2019998722 cites W1982830093 @default.
• W2019998722 cites W1989458910 @default.
• W2019998722 cites W1990358449 @default.
• W2019998722 cites W1991628500 @default.
• W2019998722 cites W2004649932 @default.
• W2019998722 cites W2006499219 @default.
• W2019998722 cites W2009745570 @default.
• W2019998722 cites W2010176612 @default.
• W2019998722 cites W2014433693 @default.
• W2019998722 cites W2016553301 @default.
• W2019998722 cites W2020538411 @default.
• W2019998722 cites W2025572547 @default.
• W2019998722 cites W2029335737 @default.
• W2019998722 cites W2034842935 @default.
• W2019998722 cites W2049775789 @default.
• W2019998722 cites W2069346964 @default.
• W2019998722 cites W2075999169 @default.
• W2019998722 cites W2080208383 @default.
• W2019998722 cites W2084021943 @default.
• W2019998722 cites W2093987948 @default.
• W2019998722 cites W2100837269 @default.
• W2019998722 cites W2121759862 @default.
• W2019998722 cites W2132860985 @default.
• W2019998722 cites W2132878122 @default.
• W2019998722 cites W2133148204 @default.
• W2019998722 cites W2134511268 @default.
• W2019998722 cites W2141522397 @default.
• W2019998722 cites W2143824972 @default.
• W2019998722 cites W2170587427 @default.
• W2019998722 cites W2174879024 @default.
• W2019998722 cites W2197332903 @default.
• W2019998722 cites W2364418961 @default.
• W2019998722 cites W4245957869 @default.
• W2019998722 doi "https://doi.org/10.1016/j.bcp.2006.03.015" @default.
• W2019998722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16624256" @default.
• W2019998722 hasPublicationYear "2006" @default.
• W2019998722 type Work @default.
• W2019998722 sameAs 2019998722 @default.
• W2019998722 citedByCount "18" @default.
• W2019998722 countsByYear W20199987222012 @default.
• W2019998722 countsByYear W20199987222013 @default.
• W2019998722 countsByYear W20199987222014 @default.
• W2019998722 countsByYear W20199987222015 @default.
• W2019998722 countsByYear W20199987222017 @default.
• W2019998722 countsByYear W20199987222018 @default.
• W2019998722 countsByYear W20199987222021 @default.
• W2019998722 crossrefType "journal-article" @default.
• W2019998722 hasAuthorship W2019998722A5018604525 @default.
• W2019998722 hasAuthorship W2019998722A5021943550 @default.
• W2019998722 hasAuthorship W2019998722A5060369739 @default.
• W2019998722 hasAuthorship W2019998722A5069021426 @default.
• W2019998722 hasAuthorship W2019998722A5073697768 @default.
• W2019998722 hasAuthorship W2019998722A5078717520 @default.
• W2019998722 hasAuthorship W2019998722A5088313319 @default.
• W2019998722 hasConcept C104317684 @default.
• W2019998722 hasConcept C105702510 @default.
• W2019998722 hasConcept C181199279 @default.
• W2019998722 hasConcept C185592680 @default.
• W2019998722 hasConcept C27256138 @default.
• W2019998722 hasConcept C2778022156 @default.
• W2019998722 hasConcept C2779179908 @default.
• W2019998722 hasConcept C2779201268 @default.
• W2019998722 hasConcept C2781324293 @default.
• W2019998722 hasConcept C3020527817 @default.
• W2019998722 hasConcept C538909803 @default.
• W2019998722 hasConcept C55493867 @default.
• W2019998722 hasConcept C62231903 @default.
• W2019998722 hasConcept C86803240 @default.
• W2019998722 hasConceptScore W2019998722C104317684 @default.
• W2019998722 hasConceptScore W2019998722C105702510 @default.
• W2019998722 hasConceptScore W2019998722C181199279 @default.
• W2019998722 hasConceptScore W2019998722C185592680 @default.
• W2019998722 hasConceptScore W2019998722C27256138 @default.
• W2019998722 hasConceptScore W2019998722C2778022156 @default.
• W2019998722 hasConceptScore W2019998722C2779179908 @default.
• W2019998722 hasConceptScore W2019998722C2779201268 @default.
• W2019998722 hasConceptScore W2019998722C2781324293 @default.
• W2019998722 hasConceptScore W2019998722C3020527817 @default.
• W2019998722 hasConceptScore W2019998722C538909803 @default.
• W2019998722 hasConceptScore W2019998722C55493867 @default.
• W2019998722 hasConceptScore W2019998722C62231903 @default.

• next