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- W2020003175 abstract "Interleukin-22 (IL-22) is an IL-10 family cytokine member that was recently discovered to be mainly produced by Th17 cells. Previous studies have indicated the importance of IL-22 in host defense against Gram-negative bacterial organisms (in gut and lung). Recently, there is emerging evidence that IL-22 is involved in the development and pathogenesis of several autoimmune diseases, such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), Sjögren's syndrome (SS) and psoriasis. Therapeutics targeting IL-22 therefore may have promise for treating various autoimmune diseases. In this review, we discuss the recent progression of the involvement of IL-22 in the development and pathogenesis of autoimmune diseases, as well as its clinical implications and therapeutic potential." @default.
- W2020003175 created "2016-06-24" @default.
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- W2020003175 date "2013-02-01" @default.
- W2020003175 modified "2023-10-03" @default.
- W2020003175 title "Emerging role of interleukin-22 in autoimmune diseases" @default.
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- W2020003175 doi "https://doi.org/10.1016/j.cytogfr.2012.07.002" @default.
- W2020003175 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4003867" @default.
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