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• W2020006790 abstract "Recent electrophysiological studies have provided evidence that GABA controls inhibitorily the activity of the serotonin containing cell bodies in nucleus dorsalis raphé (NDR). The present investigation shows that local injection of baclofen or the GABA agonist muscimol (25–100 ng) into the NDR strongly increased locomotor activity and stimulated eating in satiated rats. These effects are antagonized by the GABA antagonists bicuculline or picrotoxin given systemically or locally. Muscimol injected in NDR also decreased serotonin and 5-hydroxyindole acetic acid in hypothalamus but not in striatum. These findings support a transmitter role of GABA in NDR and may be interpreted related to a decreased activity of serotonin." @default.
• W2020006790 created "2016-06-24" @default.
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• W2020006790 date "1979-09-01" @default.
• W2020006790 modified "2023-10-18" @default.
• W2020006790 title "Evidence that GABA in the nucleus dorsalis raphé induces stimulation of locomotor activity and eating behavior" @default.
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• W2020006790 doi "https://doi.org/10.1016/0024-3205(79)90499-5" @default.
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