FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020010387> ?p ?o ?g. }

• W2020010387 endingPage "881" @default.
• W2020010387 startingPage "876" @default.
• W2020010387 abstract "l-Arginine is converted to nitric oxide and citrulline by the enzyme nitric oxide synthase (NOS). Its in vivo inhibition has led to the revelation of a multitude of diverse, often conflicting functions in the inflammatory melee. l-Arginine is also converted to ornithine and urea by the enzyme arginase as a part of the hepatic urea cycle. However, a more holistic interpretation of the two pathways and the associated metabolism (summarized in Fig. 1) has led to its reassessment as a pathologically significant enzyme. This is reflected by the continued increase over the past five years of the number of publications discussing both nitric oxide and arginase. The strong association between inflammation and high arginase and NOS activity is epitomized by immune complex-induced glomerulonephritis and other glomerulonephritides. Arginase is encoded by two recently discovered genes (Arginase I and Arginase II). There is now substantial evidence for an interaction between both arginase isoforms and all three NOS isoforms in pathological situations. This review considers the relationship between Arginases I and II and the inflammation-associated isoform of NOS called NOS II. In particular, it consolidates the current understanding of arginase and associated metabolic pathways, and highlights some of the issues that are often overlooked in such studies." @default.
• W2020010387 created "2016-06-24" @default.
• W2020010387 creator A5026999314 @default.
• W2020010387 date "2002-03-01" @default.
• W2020010387 modified "2023-09-27" @default.
• W2020010387 title "Arginase in glomerulonephritis" @default.
• W2020010387 cites W114447511 @default.
• W2020010387 cites W1541963905 @default.
• W2020010387 cites W1573977017 @default.
• W2020010387 cites W1579295790 @default.
• W2020010387 cites W1594268419 @default.
• W2020010387 cites W1855045052 @default.
• W2020010387 cites W1913781947 @default.
• W2020010387 cites W1963848198 @default.
• W2020010387 cites W1969310118 @default.
• W2020010387 cites W1972733960 @default.
• W2020010387 cites W1981785700 @default.
• W2020010387 cites W1984188855 @default.
• W2020010387 cites W1985095303 @default.
• W2020010387 cites W1991116591 @default.
• W2020010387 cites W1993630489 @default.
• W2020010387 cites W2000406927 @default.
• W2020010387 cites W200090344 @default.
• W2020010387 cites W2001810187 @default.
• W2020010387 cites W2003914506 @default.
• W2020010387 cites W2010164098 @default.
• W2020010387 cites W2011739933 @default.
• W2020010387 cites W2016647946 @default.
• W2020010387 cites W2018696161 @default.
• W2020010387 cites W2019240309 @default.
• W2020010387 cites W2021283224 @default.
• W2020010387 cites W2023772557 @default.
• W2020010387 cites W2029902056 @default.
• W2020010387 cites W2032206155 @default.
• W2020010387 cites W2036918983 @default.
• W2020010387 cites W2038992843 @default.
• W2020010387 cites W2043816868 @default.
• W2020010387 cites W2045694191 @default.
• W2020010387 cites W2048142078 @default.
• W2020010387 cites W2051994750 @default.
• W2020010387 cites W2059736568 @default.
• W2020010387 cites W2064061480 @default.
• W2020010387 cites W2085936016 @default.
• W2020010387 cites W2086592423 @default.
• W2020010387 cites W2091121269 @default.
• W2020010387 cites W2091675805 @default.
• W2020010387 cites W2098603140 @default.
• W2020010387 cites W2109708615 @default.
• W2020010387 cites W2112118882 @default.
• W2020010387 cites W2128922744 @default.
• W2020010387 cites W2133040336 @default.
• W2020010387 cites W2136415390 @default.
• W2020010387 cites W2141493942 @default.
• W2020010387 cites W2143132042 @default.
• W2020010387 cites W2152142455 @default.
• W2020010387 cites W2163175900 @default.
• W2020010387 cites W2300537100 @default.
• W2020010387 cites W2339260588 @default.
• W2020010387 cites W2340226734 @default.
• W2020010387 cites W2398759984 @default.
• W2020010387 cites W2767031288 @default.
• W2020010387 doi "https://doi.org/10.1046/j.1523-1755.2002.00236.x" @default.
• W2020010387 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11849441" @default.
• W2020010387 hasPublicationYear "2002" @default.
• W2020010387 type Work @default.
• W2020010387 sameAs 2020010387 @default.
• W2020010387 citedByCount "16" @default.
• W2020010387 countsByYear W20200103872012 @default.
• W2020010387 countsByYear W20200103872013 @default.
• W2020010387 countsByYear W20200103872015 @default.
• W2020010387 countsByYear W20200103872017 @default.
• W2020010387 countsByYear W20200103872018 @default.
• W2020010387 countsByYear W20200103872019 @default.
• W2020010387 crossrefType "journal-article" @default.
• W2020010387 hasAuthorship W2020010387A5026999314 @default.
• W2020010387 hasBestOaLocation W20200103871 @default.
• W2020010387 hasConcept C104317684 @default.
• W2020010387 hasConcept C126322002 @default.
• W2020010387 hasConcept C134018914 @default.
• W2020010387 hasConcept C164007495 @default.
• W2020010387 hasConcept C185592680 @default.
• W2020010387 hasConcept C2776796294 @default.
• W2020010387 hasConcept C2776914184 @default.
• W2020010387 hasConcept C2777468819 @default.
• W2020010387 hasConcept C2777622882 @default.
• W2020010387 hasConcept C2779129087 @default.
• W2020010387 hasConcept C2780091579 @default.
• W2020010387 hasConcept C2780368995 @default.
• W2020010387 hasConcept C515207424 @default.
• W2020010387 hasConcept C519581460 @default.
• W2020010387 hasConcept C53345823 @default.
• W2020010387 hasConcept C55493867 @default.
• W2020010387 hasConcept C71924100 @default.
• W2020010387 hasConcept C86803240 @default.
• W2020010387 hasConcept C91415057 @default.
• W2020010387 hasConceptScore W2020010387C104317684 @default.
• W2020010387 hasConceptScore W2020010387C126322002 @default.
• W2020010387 hasConceptScore W2020010387C134018914 @default.

• next